Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 3/20 | 0.45 |
| ▸ | CES1 | P23141 | 2/20 | 0.45 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7599990 | 0.86 | P2RX7 (0.48) | P2RX7CES2CES1 | |
| SCHEMBL477185 | 0.84 | MEN1 (0.53) | CES2CES1CYSLTR2CYSLTR1 | |
| SCHEMBL1435948 | 0.78 | ASAH1 (0.55) | CES2CES1 | |
| SCHEMBL29128656 | 0.78 | ASAH1 (0.55) | CES2CES1 | |
| SCHEMBL28587109 | 0.77 | LMNA (0.50) | P2RX7CES2CES1 | |
| SCHEMBL27634150 | 0.76 | ASAH1 (0.53) | CES2CES1 | |
| Heptanoate SCHEMBL6704869 | 0.74 | GPR84 (0.65) | P2RX7CES2CES1 | |
| Stearic Acid SCHEMBL11803277 | 0.74 | GPR84 (0.65) | P2RX7CES2CES1 | |
| Behenic Acid SCHEMBL28135720 | 0.74 | GPR84 (0.65) | P2RX7CES2CES1 | |
| Decanoic Acid SCHEMBL28136495 | 0.74 | GPR84 (0.65) | P2RX7CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0016582-B1 | ZIEGLER-TYPE CATALYST COMPOSITION | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1984-10-03 | — | — | EP | claimed |
| EP-0016581-B1 | ZIEGLER TYPE CATALYST COMPOSITION | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1984-08-08 | — | — | EP | claimed |
| EP-0015763-B1 | ZIEGLER TYPE CATALYST SYSTEM | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1984-05-16 | — | — | EP | claimed |
| EP-0035889-B1 | ALKYL-METAL COCATALYST | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1984-05-02 | — | — | EP | claimed |