Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2835999 | 0.88 | KMT2A (0.40) | KMT2AMEN1THRBTHRAALOX15 | |
| SCHEMBL1147837 | 0.83 | KMT2A (0.40) | KMT2AMEN1THRBTHRACHRM2 | |
| SCHEMBL4937002 | 0.81 | MEN1 (0.39) | KMT2AMEN1THRBTHRACHRM2 | |
| SCHEMBL4928619 | 0.81 | LMNA (0.46) | KMT2AMEN1ALOX15PMP22PDE3A | |
| SCHEMBL21422280 | 0.79 | MEN1 (0.37) | KMT2AMEN1THRBTHRACHRM2 | |
| Hydrochloric Acid SCHEMBL7325556 | 0.79 | LMNA (0.43) | KMT2AMEN1ALOX15BLMPMP22 | |
| SCHEMBL964734 | 0.79 | CTSD (0.45) | KMT2AMEN1THRBTHRACYP3A4 | |
| SCHEMBL1147835 | 0.76 | KMT2A (0.39) | KMT2AMEN1THRBTHRACHRM2 | |
| Ethylene Glycol SCHEMBL11520413 | 0.76 | PAOX (0.39) | KMT2AMEN1THRBTHRATDP1 | |
| SCHEMBL19085521 | 0.76 | TSHR (0.56) | KMT2AMEN1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0054593-B1 | MYOCARDIUM PROTECTING PYRROLE DERIVATIVES WITH ANTI-ARYTHMIC AND ANTI-PLATELET AGGREGATION ACTIVITY, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | SANOFI S.A. (FR) | 1985-03-13 | — | — | EP | disclosed |
| EP-0054593-A1 | Myocardium protecting pyrrole derivatives with anti-arythmic and anti-platelet aggregation activity, process for their preparation and medicines containing them | SANOFI S.A. (FR) | 1982-06-30 | — | — | EP | disclosed |
| US-4329343-A | ANTIARRYTHMIA AGENTS, BLOOD PLATELET ANTICOAGULANTS | SANOFI (FR) | 1982-05-11 | — | — | US | disclosed |