Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | KDM5C | P41229 | 1/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27793019 | 0.94 | CTSD (0.43) | CTSDALDH1A1KDM4EKDM5CPHF8 | |
| SCHEMBL962087 | 0.88 | CTSD (0.48) | CTSDALDH1A1KDM4EKDM5CPHF8 | |
| SCHEMBL11037303 | 0.79 | KMT2A (0.39) | KDM4ECYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL964918 | 0.77 | CTSD (0.50) | CTSDALDH1A1KDM4EKDM5CPHF8 | |
| SCHEMBL1147837 | 0.76 | KMT2A (0.40) | MEN1KMT2ATHRBTHRAMAPT | |
| SCHEMBL4937002 | 0.74 | MEN1 (0.39) | MEN1KMT2ATHRBTHRA | |
| SCHEMBL4928619 | 0.74 | LMNA (0.46) | ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL963418 | 0.73 | CTSD (0.52) | CTSDALDH1A1KDM4EKDM5CPHF8 | |
| SCHEMBL19085521 | 0.73 | TSHR (0.56) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL20409249 | 0.73 | FAAH (0.39) | PHF8KDM2AMEN1KMT2AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2248833-B1 | MODIFIED DIENE RUBBER, METHOD FOR PRODUCING THE SAME, RUBBER COMPOSITION USING THE SAME, AND TIRE | BRIDGESTONE CORP (JP) | 2014-03-26 | — | — | EP | disclosed |
| US-8389641-B2 | Modified diene rubber, production method thereof, and rubber composition and tire using the rubber | BRIDGESTONE CORPORATION (JP) | 2013-03-05 | — | — | US | disclosed |
| US-20110003911-A1 | MODIFIED DIENE RUBBER, PRODUCTION METHOD THEREOF, AND RUBBER COMPOSITION AND TIRE USING THE RUBBER | BRIDGESTONE CORPORATION (JP) | 2011-01-06 | — | — | US | disclosed |
| EP-2248833-A1 | MODIFIED DIENE RUBBER, METHOD FOR PRODUCING THE SAME, RUBBER COMPOSITION USING THE SAME, AND TIRE | Bridgestone Corporation (JP) | 2010-11-10 | — | — | EP | disclosed |
| US-20100249336-A1 | MODIFIED NATURAL RUBBER AND METHOD FOR PRODUCING SAME, AND RUBBER COMPOSITION AND TIRE USING SUCH A MODIFIED NATURAL RUBBER | BRIDGESTONE CORPORATION (JP) | 2010-09-30 | — | — | US | disclosed |
| EP-2206730-A1 | MODIFIED NATURAL RUBBER, PROCESS FOR PRODUCTION OF THE SAME, AND RUBBER COMPOSITION AND TIRE EACH COMPRISING THE SAME | Bridgestone Corporation (JP) | 2010-07-14 | — | — | EP | disclosed |