Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.40 |
| ▸ | CTSK | P43235 | 8/20 | 0.40 |
| ▸ | CTSS | P25774 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3851080 | 1.00 | ITGB3 (0.40) | ITGB3ITGA2BCTSKCTSSCA1 | |
| SCHEMBL2401149 | 1.00 | ITGB3 (0.40) | ITGB3ITGA2BCTSKCTSSCA1 | |
| SCHEMBL27535461 | 0.95 | CTSK (0.41) | ITGB3ITGA2BCTSKCTSSCA1 | |
| SCHEMBL8183200 | 0.87 | CTSK (0.45) | ITGB3ITGA2BCTSKCTSSCA1 | |
| SCHEMBL3818708 | 0.84 | MEN1 (0.55) | CTSKCTSSCA1CA2MEN1 | |
| SCHEMBL3498470 | 0.84 | MEN1 (0.55) | CTSKCTSSCA1CA2MEN1 | |
| SCHEMBL9515168 | 0.81 | CTSK (0.52) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL19974088 | 0.80 | CA1 (0.41) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL2427380 | 0.80 | CA1 (0.41) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL11009929 | 0.80 | CTSS (0.45) | CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0030920-B1 | ACYL PEPTIDES AND PHARMACEUTICAL PREPARATIONS THEREOF, AS WELL AS THEIR MANUFACTURE AND USE | CIBA-GEIGY AG (CH) | 1984-02-15 | — | — | EP | claimed |
| EP-0030920-A2 | Acyl peptides and pharmaceutical preparations thereof, as well as their manufacture and use | CIBA-GEIGY AG (CH) | 1981-06-24 | — | — | EP | claimed |
| CN-100355728-C | Dipeptidyl peptidase-IV inhibitors | FERRING BV (NL) | 2007-12-19 | — | — | CN | disclosed |
| CN-1839150-A | Lipopeptide antibacterial derivative composition and application method thereof | MIGENIX INC (CA) | 2006-09-27 | — | — | CN | disclosed |
| CN-1803797-A | Inhibitors of dipeptidyl peptidase IV | FERRING BV (NL) | 2006-07-19 | — | — | CN | disclosed |
| CN-1426395-A | Dipeptidyl peptidase-IV inhibitors | FERRING BV (NL) | 2003-06-25 | — | — | CN | disclosed |
| EP-0123950-A2 | Intermediates for thymosin alpha 1 and desacetylthymosin alpha 1 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-11-07 | — | — | EP | disclosed |