Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11037991 | 0.99 | ADRA1D (0.69) | ADRA1DSLC6A4 | |
| SCHEMBL11038647 | 0.99 | ADRA1D (0.69) | ADRA1DSLC6A4 | |
| SCHEMBL11038162 | 0.98 | ADRA1D (0.68) | ADRA1DSLC6A4 | |
| Hydrochloric Acid SCHEMBL11037928 | 0.97 | ADRA1D (0.69) | ADRA1DSLC6A4 | |
| SCHEMBL11047479 | 0.93 | ADRA1D (0.61) | ADRA1DSLC6A4 | |
| SCHEMBL14775605 | 0.92 | ADRA1D (0.64) | ADRA1DSLC6A4 | |
| Hydrochloric Acid SCHEMBL7649530 | 0.91 | ADRA1D (0.65) | ADRA1DSLC6A4 | |
| SCHEMBL464522 | 0.89 | ADRA1D (0.65) | ADRA1DSLC6A4 | |
| SCHEMBL11222646 | 0.85 | HTR1A (0.66) | SLC6A4 | |
| Hydrochloric Acid SCHEMBL11036620 | 0.84 | HTR1A (0.65) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0058975-B1 | SUBSTITUTED N-(4-INDOLYL-PIPERIDINO-ALKYL) BENZIMIDAZOLONES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL PREPARATIONS | Boehringer Ingelheim Pharmaceuticals Inc. (US) | 1984-12-12 | — | — | EP | claimed |
| US-4359468-A | ALSO USEFUL AS HYPOTENSIVE AGE NTS | BOEHRINGER INGELHEIM LTD. (US) | 1982-11-16 | — | — | US | claimed |
| EP-0058975-A1 | Substituted N-(4-indolyl-piperidino-alkyl) benzimidazolones, processes for their preparation and their use as pharmaceutical preparations | Boehringer Ingelheim Pharmaceuticals Inc. (US) | 1982-09-01 | — | — | EP | claimed |
| US-4359468-A | ALSO USEFUL AS HYPOTENSIVE AGE NTS | BOEHRINGER INGELHEIM LTD. (US) | 1982-11-16 | — | — | US | disclosed |
| EP-0058975-A1 | Substituted N-(4-indolyl-piperidino-alkyl) benzimidazolones, processes for their preparation and their use as pharmaceutical preparations | Boehringer Ingelheim Pharmaceuticals Inc. (US) | 1982-09-01 | — | — | EP | disclosed |