Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.66 |
| ▸ | DRD2 | P14416 | 4/20 | 0.66 |
| ▸ | HTR7 | P34969 | 4/20 | 0.66 |
| ▸ | HTR6 | P50406 | 4/20 | 0.66 |
| ▸ | HTR2A | P28223 | 3/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11036620 | 0.99 | HTR1A (0.65) | HTR1ASLC6A4DRD2HTR7HTR6 | |
| SCHEMBL11038162 | 0.87 | ADRA1D (0.68) | SLC6A4 | |
| Hydrochloric Acid SCHEMBL11037928 | 0.86 | ADRA1D (0.69) | SLC6A4 | |
| SCHEMBL11037320 | 0.85 | ADRA1D (0.67) | SLC6A4 | |
| SCHEMBL11037991 | 0.84 | ADRA1D (0.69) | SLC6A4 | |
| SCHEMBL11038647 | 0.84 | ADRA1D (0.69) | SLC6A4 | |
| SCHEMBL5937224 | 0.81 | HTR1A (0.71) | HTR1ASLC6A4DRD2HTR7HTR6 | |
| SCHEMBL11047479 | 0.81 | ADRA1D (0.61) | SLC6A4HTR7HTR2A | |
| SCHEMBL8558005 | 0.81 | HTR1A (0.77) | HTR1ASLC6A4DRD2HTR7HTR6 | |
| SCHEMBL8558622 | 0.80 | HTR1A (0.73) | HTR1ASLC6A4DRD2HTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359468-A | ALSO USEFUL AS HYPOTENSIVE AGE NTS | BOEHRINGER INGELHEIM LTD. (US) | 1982-11-16 | — | — | US | disclosed |