Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 4/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL819626 | 0.79 | ESR1 (0.56) | TRPA1TSHRMAP2K1ESR1ESR2 | |
| SCHEMBL6309534 | 0.79 | ESR1 (0.56) | TRPA1TSHRMAP2K1ESR1ESR2 | |
| SCHEMBL11206959 | 0.79 | L3MBTL1 (0.41) | TRPA1TSHRMAP2K1ESR1ESR2 | |
| SCHEMBL27946333 | 0.77 | TRPA1 (0.56) | THRBTRPA1TSHRMAP2K1ESR1 | |
| SCHEMBL955278 | 0.76 | TRPA1 (0.48) | TRPA1TSHRMAP2K1ESR1ESR2 | |
| SCHEMBL198465 | 0.74 | TSHR (0.46) | THRBTRPA1TSHRALDH1A1PBRM1 | |
| Hydrochloric Acid SCHEMBL5299628 | 0.74 | TRPA1 (0.46) | TRPA1TSHRMAP2K1ESR1ESR2 | |
| SCHEMBL198464 | 0.74 | TSHR (0.46) | THRBTRPA1TSHRALDH1A1PBRM1 | |
| SCHEMBL1343606 | 0.74 | ESR1 (0.64) | TRPA1TSHRMAP2K1ESR1ESR2 | |
| SCHEMBL27625768 | 0.74 | TSHR (0.46) | THRBTRPA1TSHRALDH1A1PBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140187545-A1 | Pyrazolopyrimidine Derivatives As PI3 Kinase Inhibitors | GLAXOSMITHKLINE LLC (US) | 2014-07-03 | — | — | US | disclosed |
| US-4438041-A | FROM A CYANOACETALDEHYDE ACETAL, HYDROXYLAMINE, AND AN ALCOHOL | UBE INDUSTRIES, LTD. (JP) | 1984-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140187545-A1 | Pyrazolopyrimidine Derivatives As PI3 Kinase Inhibitors | PI4KB, PIK3CA, PI4K2B | THRB 797/4885TRPA1 4690/4885TSHR 3253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.