Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL198464 | 1.00 | TSHR (0.46) | TSHRTRPA1THRBALDH1A1PBRM1 | |
| SCHEMBL27625768 | 1.00 | TSHR (0.46) | TSHRTRPA1THRBALDH1A1PBRM1 | |
| Pentane SCHEMBL28983044 | 0.89 | TRPA1 (0.38) | TSHRTRPA1THRBALDH1A1PBRM1 | |
| SCHEMBL28141083 | 0.86 | TRPA1 (0.36) | TSHRTRPA1ALDH1A1PBRM1KMT2A | |
| SCHEMBL1199568 | 0.83 | TRPA1 (0.43) | TSHRTRPA1THRBALDH1A1PBRM1 | |
| SCHEMBL21114422 | 0.81 | TSHR (0.50) | TSHRTRPA1ALDH1A1PBRM1AKR1C3 | |
| SCHEMBL3968014 | 0.81 | TSHR (0.50) | TSHRTRPA1ALDH1A1PBRM1AKR1C3 | |
| SCHEMBL5684868 | 0.80 | ALDH1A1 (0.31) | ALDH1A1GAA | |
| SCHEMBL2162532 | 0.79 | TSHR (0.48) | TSHRTRPA1ALDH1A1PBRM1AKR1C3 | |
| SCHEMBL27539710 | 0.79 | TSHR (0.48) | TSHRTRPA1ALDH1A1PBRM1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290242-A | Synthesis method of chickpea sprout element A intermediate | 浙江广厦建设职业技术大学 | 2024-07-05 | — | — | CN | claimed |
| CN-112920062-B | Method for synthesizing venlafaxine by utilizing fixed bed hydrogenation equipment | 合肥立方制药股份有限公司 | 2024-04-02 | — | — | CN | claimed |
| US-20160068506-A1 | COMBRETASTATIN ANALOGS | BIOVENTURES, LLC | 2016-03-10 | — | — | US | claimed |
| CN-103483210-B | A kind of new compound and preparation method thereof | CHENGDU HONGDA PHARMACEUTICAL CO., LTD. (CN) | 2016-01-13 | — | — | CN | claimed |
| EP-2327766-B1 | Nitrilases | BASF ENZYMES LLC (US) | 2015-12-02 | — | — | EP | claimed |
| EP-2319919-B1 | Nitrilases | BASF ENZYMES LLC (US) | 2015-08-12 | — | — | EP | claimed |
| EP-2327767-B1 | Nitrilases | BASF ENZYMES LLC (US) | 2015-04-29 | — | — | EP | claimed |
| EP-2327765-B1 | Nitrilases | BASF ENZYMES LLC (US) | 2015-04-01 | — | — | EP | claimed |
| CN-103483210-A | New compound and preparation method thereof | CHENGDU HONGDA PHARMACEUTICAL CO LTD | 2014-01-01 | — | — | CN | claimed |
| US-20130177949-A1 | NITRILASES | VERENIUM CORPORATION (US) | 2013-07-11 | — | — | US | claimed |
| EP-2039762-A2 | Nitralases | Verenium Corporation (US) | 2009-03-25 | — | — | EP | claimed |
| EP-1578910-A4 | NITRILASES | VERENIUM CORP (US) | 2008-06-04 | — | — | EP | claimed |
| US-20060259999-A1 | Modified nitrilases and their use in methods for the production of carboxylic acids | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-16 | — | — | US | claimed |
| CN-1267410-C | Process for preparing cyclohexanol derivatives | WYETH CORP (US) | 2006-08-02 | — | — | CN | claimed |
| EP-1578910-A2 | NITRILASES | DIVERSA CORPORATION (US) | 2005-09-28 | — | — | EP | claimed |
| CN-1531524-A | Process for preparing cyclohexanol derivatives | — | 2004-09-22 | — | — | CN | claimed |
| US-20030124698-A1 | Which stereoselectively hydrolyze nitrites or cyanohydrins into acids and ammonia | DIVERSA CORPORATION | 2003-07-03 | — | — | US | claimed |
| WO-2003050074-A1 | MANUFACTURE OF VENLAFAXINE HYDROCHLORIDE AND CRYSTALLINE POLYMORPHS THEREOF | CADILA HEALTHCARE LIMITED (IN) | 2003-06-19 | — | — | WO | claimed |
| WO-2003000840-A2 | NITRILASES | DIVERSA CORPORATION (US) | 2003-01-03 | — | — | WO | claimed |
| US-4307034-A | ALKYLATION | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1981-12-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030124698-A1 | Which stereoselectively hydrolyze nitrites or cyanohydrins into acids and ammonia | NIT2, DNPH1, ASNS | TSHR 4562/4885TRPA1 2608/4885THRB 3402/4885 |
| US-20160068506-A1 | COMBRETASTATIN ANALOGS | HDAC6, HDAC11, HDAC5 | TSHR 3987/4885TRPA1 4723/4885THRB 2277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.