Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 7/20 | 0.61 |
| ▸ | MCHR1 | Q99705 | 9/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | BMP4 | P12644 | 1/20 | 0.44 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10417253 | 0.77 | MAPKAPK2 (0.70) | MAPKAPK2RAB9A | |
| SCHEMBL8206418 | 0.77 | MAPKAPK2 (0.70) | MAPKAPK2RAB9A | |
| SCHEMBL10540093 | 0.72 | ABCB11 (0.62) | MCHR1ESR1RIPK2NOD2 | |
| SCHEMBL6831337 | 0.72 | MCHR1 (0.53) | MCHR1ESR1 | |
| SCHEMBL12440415 | 0.70 | MCHR1 (0.73) | MCHR1RAB9AESR1BMP4 | |
| SCHEMBL12440250 | 0.69 | MCHR1 (0.68) | MCHR1ESR1 | |
| SCHEMBL9706125 | 0.68 | EBP (0.72) | MCHR1ESR1 | |
| SCHEMBL10970158 | 0.68 | MCHR1 (0.91) | MCHR1ESR1 | |
| SCHEMBL30615777 | 0.67 | MEN1 (0.65) | MCHR1RAB9AESR1 | |
| SCHEMBL26914701 | 0.67 | MCHR1 (0.51) | MCHR1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178035-A1 | Anti-inflammatory 1,N-diarylpyrazol-3-amines, compositions containing them and processes for their preparation | FISONS plc (GB) | 1986-04-16 | — | — | EP | claimed |