Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 6/20 | 0.70 |
| ▸ | RAB9A | P51151 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | SRC | P12931 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | ABL2 | P42684 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10417253 | 0.86 | MAPKAPK2 (0.70) | MAPKAPK2RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL3852847 | 0.84 | RAB9A (0.58) | MAPKAPK2RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL11837756 | 0.82 | RAB9A (0.72) | MAPKAPK2RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL11766305 | 0.81 | RAB9A (1.00) | MAPKAPK2RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL8206667 | 0.80 | NPC1 (0.58) | RAB9AMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL11765458 | 0.80 | RAB9A (0.82) | MAPKAPK2RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL4186718 | 0.79 | RAB9A (0.65) | RAB9AMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL17619706 | 0.78 | PTGS2 (0.51) | MAPKAPK2RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL11762985 | 0.77 | RAB9A (0.81) | MAPKAPK2RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL11037574 | 0.77 | MAPKAPK2 (0.61) | MAPKAPK2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008046527-A1 | ACYLAMINOPYRAZOLES FOR TREATING CARDIOVASCULAR DISEASES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-04-24 | — | — | WO | disclosed |