Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | LPL | P06858 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12933493 | 0.87 | LPL (0.46) | ESR1LPLLIPGCA2 | |
| SCHEMBL9969769 | 0.85 | CA2 (0.52) | ESR1ESR2LPLLIPGCA2 | |
| SCHEMBL9331806 | 0.82 | ALDH1A1 (0.44) | ESR1ESR2LTA4HHDAC1CA2 | |
| SCHEMBL12354628 | 0.81 | CA2 (0.46) | ESR1ESR2LTA4HCA2HDAC8 | |
| SCHEMBL9888590 | 0.78 | TP53 (0.43) | HDAC1LPLLIPGCA2HDAC3 | |
| SCHEMBL4301035 | 0.78 | HRH3 (0.50) | CA2HDAC3HDAC6 | |
| SCHEMBL12531870 | 0.78 | CA1 (0.38) | CA2 | |
| SCHEMBL1641222 | 0.78 | FFAR1 (0.59) | FFAR1CA2 | |
| SCHEMBL9335050 | 0.78 | CA2 (0.49) | ESR1LTA4HHDAC1LPLLIPG | |
| SCHEMBL2561048 | 0.72 | KMT2A (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151800-A2 | Use of urethane-modified polyisocyanate products as an isocyanate component in the preparation of molded resins according to the RIM-technique | BAYER AG (DE) | 1985-08-21 | — | — | EP | disclosed |