2-Pyrrolidone

2-Pyrrolidone

SCHEMBL11038232

O=C1CCCN1.O=C1CCCN1CCc1ccccc1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.48
ACHE P22303 2/20 0.47
RAB9A P51151 2/20 0.46
NPC1 O15118 1/20 0.46
ALB P02768 1/20 0.45
BCHE P06276 1/20 0.45
SMN1; SMN2 Q16637 3/20 0.44
GAA P10253 2/20 0.44
MCHR1 Q99705 1/20 0.43
TSHR P16473 2/20 0.43
MAPT P10636 1/20 0.42
KMT2A Q03164 1/20 0.42
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2132367 0.87 L3MBTL1 (0.60) L3MBTL1ACHERAB9ANPC1SMN1; SMN2
2-Pyrrolidone SCHEMBL11025581 0.86 L3MBTL1 (0.66) L3MBTL1ACHESMN1; SMN2GAAKMT2A
SCHEMBL917005 0.82 L3MBTL1 (0.68) L3MBTL1ACHERAB9ANPC1SMN1; SMN2
SCHEMBL5872163 0.81 L3MBTL1 (0.71) L3MBTL1ACHERAB9ANPC1SMN1; SMN2
SCHEMBL8882276 0.78 L3MBTL1 (0.57) L3MBTL1ACHERAB9ANPC1SMN1; SMN2
SCHEMBL11513541 0.77 NPC1 (0.58) L3MBTL1ACHERAB9ANPC1GAA
2-Pyrrolidone SCHEMBL17595381 0.77 OR51E2 (0.48) GAATSHRKMT2AKDM4E
SCHEMBL28535700 0.74 ALB (0.49) L3MBTL1ACHEALBBCHEGAA
SCHEMBL28547803 0.74 MCHR1 (0.47) L3MBTL1ACHERAB9ANPC1SMN1; SMN2
2-Pyrrolidone SCHEMBL6940458 0.74 OR51E2 (0.46) RAB9ANPC1SMN1; SMN2GAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0095822-B1 HYDROGEN PEROXIDE PROCESS FMC Corporation (US) 1985-06-12 EP claimed