Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2132367 | 0.89 | L3MBTL1 (0.60) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL917005 | 0.87 | L3MBTL1 (0.68) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL5872163 | 0.86 | L3MBTL1 (0.71) | NPC1RAB9AMAPTL3MBTL1GAA | |
| SCHEMBL10750812 | 0.86 | GAA (0.51) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL4283301 | 0.80 | KMT2A (0.56) | KMT2AMEN1MAPTL3MBTL1GAA | |
| SCHEMBL7389188 | 0.80 | L3MBTL1 (0.73) | NPC1RAB9AKMT2AMEN1L3MBTL1 | |
| SCHEMBL8882276 | 0.79 | L3MBTL1 (0.57) | NPC1RAB9AKMT2AL3MBTL1GAA | |
| SCHEMBL22623804 | 0.79 | DDB1 (0.71) | KMT2AMEN1MAPTL3MBTL1GAA | |
| SCHEMBL931348 | 0.78 | SIGMAR1 (0.49) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL11432099 | 0.78 | SIGMAR1 (0.60) | NPC1KMT2AMEN1GAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4178286-A | β-Lactams, their production, intermediates thereto and derivatives thereof | RESEARCH CORPORATION (US) | 1979-12-11 | — | — | US | disclosed |
| US-4163743-A | Beta-lactams, their production from azetidine carboxylic acids, intermediates thereto and derivatives thereof | RESEARCH CORPORATION (US) | 1979-08-07 | — | — | US | disclosed |