Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5872083 | 0.94 | L3MBTL1 (0.67) | L3MBTL1SIGMAR1KMT2AACHEGAA | |
| SCHEMBL2132367 | 0.90 | L3MBTL1 (0.60) | L3MBTL1KMT2AACHEGAASMN1; SMN2 | |
| SCHEMBL18836848 | 0.85 | SIGMAR1 (0.52) | L3MBTL1SIGMAR1KMT2AGAASMN1; SMN2 | |
| SCHEMBL917005 | 0.85 | L3MBTL1 (0.68) | L3MBTL1SIGMAR1KMT2AACHEGAA | |
| SCHEMBL13639218 | 0.84 | RAB9A (0.49) | KMT2ASMN1; SMN2TSHRRAB9AKDM4E | |
| SCHEMBL10504904 | 0.84 | KMT2A (0.48) | L3MBTL1ADRA1BKMT2AGAATSHR | |
| SCHEMBL13946711 | 0.84 | RAB9A (0.55) | L3MBTL1ADRA1BKMT2ANPC1RAB9A | |
| SCHEMBL5872163 | 0.83 | L3MBTL1 (0.71) | L3MBTL1SIGMAR1ACHEGAASMN1; SMN2 | |
| SCHEMBL17117358 | 0.83 | SIGMAR1 (0.56) | SIGMAR1GRIN2BSLC6A3 | |
| SCHEMBL12518392 | 0.82 | SIGMAR1 (0.53) | L3MBTL1SIGMAR1KMT2ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |