Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 6/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.52 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | HTR2B | P41595 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.52 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.52 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16789571 | 0.85 | GABRA1 (0.56) | GABRA1GABRB2GABRB1LMNASLC6A2 | |
| SCHEMBL5394172 | 0.83 | LMNA (0.52) | GABRA1GABRB2GABRB1LMNASLC6A2 | |
| SCHEMBL29849603 | 0.83 | LMNA (0.52) | GABRA1GABRB2GABRB1LMNASLC6A2 | |
| SCHEMBL15011592 | 0.81 | LMNA (0.50) | GABRA1GABRB2GABRB1LMNASLC6A2 | |
| SCHEMBL366229 | 0.81 | GABRA1 (0.52) | GABRA1GABRB2GABRB1LMNASLC6A2 | |
| SCHEMBL487169 | 0.80 | GABRA1 (0.56) | GABRA1GABRB2GABRB1LMNASLC6A2 | |
| SCHEMBL9497827 | 0.79 | TYR (0.40) | LMNASLC6A2HTR2BTRPA1CHRM1 | |
| SCHEMBL1981588 | 0.79 | LMNA (0.48) | GABRA1GABRB2GABRB1LMNASLC6A2 | |
| SCHEMBL9556357 | 0.79 | GABRA1 (0.50) | GABRA1GABRB2GABRB1LMNASLC6A2 | |
| SCHEMBL29699645 | 0.79 | GABRA1 (0.68) | GABRA1GABRB2GABRB1LMNASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170144965-A1 | MARMELIN ANALOGS AND METHODS OF USE IN CANCER TREATMENT | THE UNIVERSITY OF KANSAS | 2017-05-25 | — | — | US | disclosed |
| EP-0076221-B1 | PROCESS FOR THE ETHERIFICATION OF PHENOLS | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1985-05-02 | — | — | EP | disclosed |
| EP-0037353-B1 | PROCESS FOR THE ETHERIFICATION OF PHENOLS | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1983-06-08 | — | — | EP | disclosed |
| EP-0076221-A1 | Process for the etherification of phenols | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1983-04-06 | — | — | EP | disclosed |
| EP-0046719-A1 | Process for the etherification of phenols | RHONE-POULENC INDUSTRIES (FR) | 1982-03-03 | — | — | EP | disclosed |
| EP-0037353-A1 | Process for the etherification of phenols | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1981-10-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170144965-A1 | MARMELIN ANALOGS AND METHODS OF USE IN CANCER TREATMENT | COIL, MUC1, MAN2B2 | GABRA1 3312/4885GABRB2 2465/4885GABRB1 2250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.