Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1533850 | 0.83 | BRD4 (0.53) | ACHEBRD4KDM4EALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL11040765 | 0.75 | TSHR (0.36) | ACHEKDM4EALDH1A1PDE4DTSHR | |
| SCHEMBL11043204 | 0.75 | BRD4 (0.44) | BRD4KDM4EALDH1A1CYP3A4LMNA | |
| SCHEMBL11041593 | 0.73 | GAA (0.51) | ACHEBRD4KDM4EALDH1A1TP53 | |
| SCHEMBL11057303 | 0.71 | MAPT (0.40) | BRD4KDM4EALDH1A1PDE4DTSHR | |
| SCHEMBL11040367 | 0.71 | MAPT (0.40) | BRD4KDM4EALDH1A1PDE4DTSHR | |
| Hydrochloric Acid SCHEMBL11059748 | 0.71 | MAPT (0.42) | BRD4KDM4EALDH1A1PDE4DTSHR | |
| Hydrochloric Acid SCHEMBL11051850 | 0.71 | MAPT (0.42) | BRD4KDM4EALDH1A1PDE4DTSHR | |
| SCHEMBL11039717 | 0.69 | BRD4 (0.41) | BRD4KDM4EALDH1A1PDE4DTSHR | |
| SCHEMBL24465258 | 0.68 | MAPT (0.52) | ACHEKDM4EALDH1A1TP53MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116444-A2 | Improvements in or relating to benzazepine derivatives | ELI LILLY AND COMPANY (US) | 1984-08-22 | — | — | EP | disclosed |