Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | BPTF | Q12830 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11057303 | 1.00 | MAPT (0.40) | MAPTKDM4EGAAMAPK1BRD4 | |
| Hydrochloric Acid SCHEMBL11051850 | 0.99 | MAPT (0.42) | MAPTKDM4EGAAMAPK1BRD4 | |
| Hydrochloric Acid SCHEMBL11059748 | 0.99 | MAPT (0.42) | MAPTKDM4EGAAMAPK1BRD4 | |
| Hydrochloric Acid SCHEMBL11040765 | 0.93 | TSHR (0.36) | MAPTKDM4EGAAMAPK1PDE4D | |
| SCHEMBL11041640 | 0.90 | BRD4 (0.45) | MAPTKDM4EGAAMAPK1BRD4 | |
| Hydrochloric Acid SCHEMBL11040043 | 0.89 | BRD4 (0.44) | MAPTKDM4EGAAMAPK1BRD4 | |
| SCHEMBL11039717 | 0.82 | BRD4 (0.41) | MAPTKDM4EGAAMAPK1BRD4 | |
| Hydrochloric Acid SCHEMBL11038881 | 0.79 | BRD4 (0.38) | MAPTGAABRD4CYP3A4 | |
| Hydrochloric Acid SCHEMBL11042874 | 0.78 | BRD4 (0.38) | MAPTBRD4CYP3A4ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL11038894 | 0.78 | MAOA (0.38) | MAPTBRD4CYP3A4LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116444-A2 | Improvements in or relating to benzazepine derivatives | ELI LILLY AND COMPANY (US) | 1984-08-22 | — | — | EP | claimed |