SCHEMBL11039015

SCHEMBL11039015

C=CC(CC)(Cc1ccc(Cl)cc1)C(C)=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.41
SLC6A2 P23975 1/20 0.40
HTR2A P28223 1/20 0.40
SLC6A4 P31645 1/20 0.40
HRH1 P35367 1/20 0.40
HTR2B P41595 1/20 0.40
CHRNA4 P43681 1/20 0.40
SLC6A3 Q01959 1/20 0.40
CYP3A4 P08684 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
NFKB1 P19838 1/20 0.38
CYP2C19 P33261 1/20 0.38
TEAD1 P28347 1/20 0.38
LMNA P02545 3/20 0.38
PMP22 Q01453 1/20 0.38
NLRP3 Q96P20 1/20 0.38
THRA P10827 1/20 0.37
THRB P10828 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11043536 0.84 ALDH1A1 (0.46) SLC6A2CYP3A4CYP1A2CYP2C9CYP2C19
SCHEMBL11040943 0.82 SMN1; SMN2 (0.44) CYP3A4HTTSMN1; SMN2CTSKALDH1A1
SCHEMBL11039404 0.78 SLC6A4 (0.46) L3MBTL1SLC6A2HTR2ASLC6A4HRH1
SCHEMBL11040009 0.72 ALDH1A1 (0.44) SLC6A2CYP3A4CYP1A2CYP2C9CYP2C19
SCHEMBL11039064 0.72 HPGD (0.40) CYP1A2CYP2C19LMNATHRATHRB
SCHEMBL10383881 0.71 SLC6A4 (0.53) L3MBTL1SLC6A2HTR2ASLC6A4HRH1
SCHEMBL11043144 0.71 SMN1; SMN2 (0.41) CYP3A4THRBHTTSMN1; SMN2CTSK
SCHEMBL11039808 0.70 ALDH1A1 (0.42) SLC6A2CYP3A4CYP1A2CYP2C9CYP2C19
SCHEMBL11039810 0.70 ALDH1A1 (0.42) SLC6A2CYP3A4CYP1A2CYP2C9CYP2C19
SCHEMBL11040868 0.70 ALDH1A1 (0.42) CYP3A4CYP2C9CYP2C19THRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0038471-B1 BETA-GAMMA-UNSATURATED KETONES AND ISOPRENOIC DIENONES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PERFUME COMPOUNDS AND FLAVOURINGS Consortium für elektrochemische Industrie GmbH (DE) 1984-11-14 EP disclosed
US-4385185-A β-γ-Unsaturated ketones and isoprenoid 2,6 diones, a process for producing the same and their use as fragrant and flavoring substances CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1983-05-24 US disclosed
EP-0038471-A1 Beta-gamma-unsaturated ketones and isoprenoic dienones, process for their preparation and their use as perfume compounds and flavourings Consortium für elektrochemische Industrie GmbH (DE) 1981-10-28 EP disclosed