SCHEMBL11040943

SCHEMBL11040943

C=CC(CC)(Cc1ccc(OC)cc1)C(C)=O

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.44
ALDH1A1 P00352 2/20 0.44
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44
ALOX12 P18054 1/20 0.44
HTT P42858 1/20 0.41
LDHA P00338 1/20 0.41
CTBP2 P56545 1/20 0.40
EPHX2 P34913 1/20 0.40
F2RL1 P55085 1/20 0.40
PKM P14618 1/20 0.39
APLNR P35414 1/20 0.39
TSPO P30536 1/20 0.39
TGM2 P21980 1/20 0.39
CTSK P43235 1/20 0.39
BCL2A1 Q16548 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11043144 0.89 SMN1; SMN2 (0.41) SMN1; SMN2ALDH1A1TP53CYP3A4ALOX15
SCHEMBL11039015 0.82 L3MBTL1 (0.41) SMN1; SMN2ALDH1A1CYP3A4HTTCTBP2
SCHEMBL11043536 0.81 ALDH1A1 (0.46) SMN1; SMN2ALDH1A1CYP3A4CTSK
SCHEMBL11039805 0.79 SMN1; SMN2 (0.46) SMN1; SMN2ALDH1A1TP53CYP3A4ALOX15
SCHEMBL8039407 0.73 ALDH1A1 (0.50) SMN1; SMN2ALDH1A1HTTLDHACTBP2
SCHEMBL24734363 0.73 SMN1; SMN2 (0.49) SMN1; SMN2HTTLDHAEPHX2F2RL1
SCHEMBL20269317 0.73 SMN1; SMN2 (0.49) SMN1; SMN2HTTLDHAEPHX2F2RL1
SCHEMBL9392395 0.71 SMN1; SMN2 (0.47) SMN1; SMN2HTTLDHACTBP2EPHX2
SCHEMBL16740537 0.71 ALDH1A1 (0.47) SMN1; SMN2ALDH1A1TP53CYP3A4ALOX15
SCHEMBL10786742 0.71 ALDH1A1 (0.55) SMN1; SMN2ALDH1A1TP53CYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0038471-B1 BETA-GAMMA-UNSATURATED KETONES AND ISOPRENOIC DIENONES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PERFUME COMPOUNDS AND FLAVOURINGS Consortium für elektrochemische Industrie GmbH (DE) 1984-11-14 EP disclosed
US-4385185-A β-γ-Unsaturated ketones and isoprenoid 2,6 diones, a process for producing the same and their use as fragrant and flavoring substances CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1983-05-24 US disclosed
EP-0038471-A1 Beta-gamma-unsaturated ketones and isoprenoic dienones, process for their preparation and their use as perfume compounds and flavourings Consortium für elektrochemische Industrie GmbH (DE) 1981-10-28 EP disclosed