SCHEMBL11039031

SCHEMBL11039031

CCOc1ccc(C(=O)OC)c(S(=O)(=O)NC(=O)Nc2ncc(OC)c(OC(F)F)n2)c1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
TSHR P16473 1/20 0.35
RAB9A P51151 1/20 0.35
KDM4E B2RXH2 2/20 0.35
ALDH1A1 P00352 2/20 0.35
FBP1 P09467 2/20 0.35
NPC1 O15118 1/20 0.35
GAA P10253 1/20 0.35
CDK1 P06493 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
TDP1 Q9NUW8 1/20 0.34
RCE1 Q9Y256 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9835685 0.84 GAA (0.48) MAPTKDM4EALDH1A1NPC1GAA
SCHEMBL9814932 0.79 ALDH1A1 (0.47) MAPTKDM4EALDH1A1NPC1GAA
SCHEMBL9833453 0.77 GAA (0.48) MAPTMEN1KMT2ATSHRKDM4E
SCHEMBL10519893 0.76 GAA (0.50) MAPTKDM4EALDH1A1FBP1GAA
SCHEMBL9199568 0.74 CDK1 (0.39) MEN1KMT2ATSHRKDM4EALDH1A1
SCHEMBL11384571 0.71 CDK1 (0.40) MAPTMEN1KMT2ATSHRKDM4E
SCHEMBL9827880 0.70 GAA (0.54) MAPTKMT2AFBP1GAACDK1
SCHEMBL10532270 0.68 POLB (0.43) MAPTMEN1KMT2ARAB9AKDM4E
SCHEMBL11359430 0.68 GAA (0.36) MEN1KMT2ATSHRKDM4EALDH1A1
SCHEMBL9140753 0.68 GAA (0.48) MAPTMEN1KMT2ANPC1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0162723-A2 Herbicidal sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-11-27 EP disclosed