Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9833453 | 0.93 | GAA (0.48) | GAACDK1MAPTNPC1ALDH1A1 | |
| SCHEMBL10519893 | 0.88 | GAA (0.50) | GAACDK1MAPTALDH1A1KDM4E | |
| SCHEMBL9467729 | 0.84 | GAA (0.53) | GAACDK1MAPTNPC1TP53 | |
| SCHEMBL11039031 | 0.84 | MAPT (0.36) | GAACDK1MAPTNPC1ALDH1A1 | |
| SCHEMBL9827880 | 0.83 | GAA (0.54) | GAACDK1MAPTTP53GLA | |
| SCHEMBL9814932 | 0.83 | ALDH1A1 (0.47) | GAACDK1MAPTNPC1ALDH1A1 | |
| SCHEMBL10455589 | 0.82 | GAA (0.53) | GAACDK1MAPTNPC1ALDH1A1 | |
| SCHEMBL29508602 | 0.81 | GAA (0.48) | GAACDK1MAPTNPC1 | |
| SCHEMBL9140753 | 0.81 | GAA (0.48) | GAACDK1MAPTNPC1 | |
| SCHEMBL118690 | 0.81 | GAA (0.48) | GAACDK1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0162723-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-05-29 | — | — | EP | disclosed |
| US-4877442-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-10-31 | — | — | US | disclosed |