Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10532270 | 0.85 | POLB (0.43) | ALDH1A1KDM4ENPC1MAPTCDK1 | |
| SCHEMBL10853805 | 0.84 | CDK1 (0.43) | ALDH1A1KDM4ENPC1MAPTCDK1 | |
| SCHEMBL11372353 | 0.84 | CDK1 (0.46) | ALDH1A1KDM4ENPC1MAPTCDK1 | |
| SCHEMBL9835685 | 0.83 | GAA (0.48) | ALDH1A1KDM4ENPC1MAPTCDK1 | |
| SCHEMBL9244901 | 0.81 | MAPT (0.41) | ALDH1A1KDM4ENPC1MAPTCDK1 | |
| SCHEMBL7023958 | 0.80 | NPC1 (0.50) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL11039031 | 0.79 | MAPT (0.36) | ALDH1A1KDM4ENPC1MAPTCDK1 | |
| SCHEMBL8011325 | 0.79 | CDK1 (0.43) | ALDH1A1KDM4ENPC1MAPTCDK1 | |
| SCHEMBL11380190 | 0.78 | CDK1 (0.43) | ALDH1A1KDM4ENPC1MAPTCDK1 | |
| SCHEMBL11184973 | 0.78 | ALDH1A1 (0.52) | ALDH1A1KDM4ENPC1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0162723-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-05-29 | — | — | EP | disclosed |
| US-4981509-A | Plant growth regulators | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-01-01 | — | — | US | disclosed |
| US-4871847-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-10-03 | — | — | US | disclosed |
| US-4849010-A | Herbicidal sulfonamides | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1989-07-18 | — | — | US | disclosed |
| US-4724039-A | RICE CROP | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-02-09 | — | — | US | disclosed |
| US-4710221-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-12-01 | — | — | US | disclosed |
| EP-0162723-A2 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-11-27 | — | — | EP | disclosed |