Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 5/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.53 |
| ▸ | CTSC | P53634 | 1/20 | 0.52 |
| ▸ | YARS1 | P54577 | 2/20 | 0.51 |
| ▸ | MC4R | P32245 | 1/20 | 0.51 |
| ▸ | MC3R | P41968 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27182753 | 0.85 | SLC7A5 (0.50) | OPRD1OPRM1OPRK1SLC7A5YARS1 | |
| SCHEMBL29608649 | 0.82 | MME (0.59) | OPRD1OPRM1OPRK1 | |
| SCHEMBL29802611 | 0.82 | ENPEP (0.60) | OPRD1OPRM1OPRK1 | |
| SCHEMBL9752001 | 0.82 | MAPK1 (0.62) | SLC7A5CTSCMC4RMC3R | |
| SCHEMBL27182846 | 0.82 | MAPK1 (0.62) | SLC7A5CTSCMC4RMC3R | |
| SCHEMBL7457031 | 0.82 | MAPK1 (0.62) | SLC7A5CTSCMC4RMC3R | |
| SCHEMBL30966066 | 0.81 | — | — | |
| SCHEMBL24453079 | 0.81 | MAPK1 (0.69) | SLC7A5CTSCMC4RMC3R | |
| SCHEMBL13669592 | 0.81 | MAPK1 (0.69) | SLC7A5CTSCMC4RMC3R | |
| SCHEMBL9822661 | 0.81 | SLC7A5 (0.59) | OPRD1OPRM1OPRK1SLC7A5YARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0077274-B1 | 3-AMINO-2-HYDROXY-4-PHENYLBUTANOIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1985-08-28 | — | — | EP | disclosed |
| US-4474764-A | ANALGESICS | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1984-10-02 | — | — | US | disclosed |
| EP-0077274-A1 | 3-Amino-2-hydroxy-4-phenylbutanoic acid derivatives and pharmaceutical composition containing the same | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1983-04-20 | — | — | EP | disclosed |