Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CTSC | P53634 | 2/20 | 0.52 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.49 |
| ▸ | MC4R | P32245 | 1/20 | 0.48 |
| ▸ | MC3R | P41968 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 5/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.47 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.47 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.47 |
| ▸ | PRKX | P51817 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27182846 | 1.00 | MAPK1 (0.62) | MAPK1CYP3A4CTSCSLC15A1MC4R | |
| SCHEMBL7457031 | 1.00 | MAPK1 (0.62) | MAPK1CYP3A4CTSCSLC15A1MC4R | |
| SCHEMBL24453079 | 0.91 | MAPK1 (0.69) | MAPK1CYP3A4CTSCSLC15A1MC4R | |
| SCHEMBL13669592 | 0.91 | MAPK1 (0.69) | MAPK1CYP3A4CTSCSLC15A1MC4R | |
| SCHEMBL27182753 | 0.89 | SLC7A5 (0.50) | MAPK1CYP3A4SLC7A5 | |
| SCHEMBL27471057 | 0.86 | CYP3A4 (0.68) | MAPK1CYP3A4CTSCLTA4H | |
| SCHEMBL12228016 | 0.83 | CYP3A4 (0.47) | MAPK1CYP3A4CTSCSLC15A1SLC7A5 | |
| SCHEMBL10558069 | 0.82 | MAPK1 (0.75) | MAPK1CYP3A4CTSCROCK2RPS6KA5 | |
| SCHEMBL11039145 | 0.82 | OPRD1 (0.53) | CTSCMC4RMC3RSLC7A5 | |
| SCHEMBL10632506 | 0.81 | SLC15A1 (0.58) | CTSCSLC15A1ALPIPKMPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449884-A4 | DERIVATIVES OF TETRAPEPTIDES AS CCK AGONISTS | — | 1991-10-30 | — | — | EP | disclosed |
| EP-0449884-A1 | DERIVATIVES OF TETRAPEPTIDES AS CCK AGONISTS | ABBOTT LABORATORIES (US) | 1991-10-09 | — | — | EP | disclosed |