Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | CTSC | P53634 | 2/20 | 0.61 |
| ▸ | ALPI | P09923 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | XIAP | P98170 | 1/20 | 0.58 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.58 |
| ▸ | MC4R | P32245 | 1/20 | 0.55 |
| ▸ | MC3R | P41968 | 1/20 | 0.55 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.51 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.51 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.51 |
| ▸ | PRKACA | P17612 | 1/20 | 0.51 |
| ▸ | GSK3A | P49840 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13669592 | 1.00 | MAPK1 (0.69) | MAPK1CYP3A4CTSCALPIPKM | |
| SCHEMBL7457031 | 0.91 | MAPK1 (0.62) | MAPK1CYP3A4CTSCALPIPKM | |
| SCHEMBL9752001 | 0.91 | MAPK1 (0.62) | MAPK1CYP3A4CTSCALPIPKM | |
| SCHEMBL27182846 | 0.91 | MAPK1 (0.62) | MAPK1CYP3A4CTSCALPIPKM | |
| SCHEMBL27471057 | 0.88 | CYP3A4 (0.68) | MAPK1CYP3A4CTSCLTA4H | |
| SCHEMBL10558069 | 0.87 | MAPK1 (0.75) | MAPK1CYP3A4CTSCROCK2ROCK1 | |
| SCHEMBL9572331 | 0.84 | CYP3A4 (0.55) | MAPK1CYP3A4CTSCALPIPKM | |
| SCHEMBL11211282 | 0.84 | MME (0.65) | MAPK1CYP3A4CTSCALPIPKM | |
| SCHEMBL22567078 | 0.84 | CTSC (0.58) | MAPK1CYP3A4CTSCALPIPKM | |
| SCHEMBL11211279 | 0.84 | MME (0.65) | MAPK1CYP3A4CTSCALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11447448-B2 | Process for the preparation of solriamfetol and salt thereof | GLENMARK LIFE SCIENCES LIMITED (IN) | 2022-09-20 | — | — | US | disclosed |
| US-20220162159-A1 | PROCESS FOR THE PREPARATION OF SOLRIAMFETOL AND SALT THEREOF | ALIVUS LIFE SCIENCES LIMITED (IN) | 2022-05-26 | — | — | US | disclosed |
| US-20220162159-A1 | PROCESS FOR THE PREPARATION OF SOLRIAMFETOL AND SALT THEREOF | ALIVUS LIFE SCIENCES LIMITED (IN) | 2022-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220162159-A1 | PROCESS FOR THE PREPARATION OF SOLRIAMFETOL AND SALT THEREOF | TST, SPR, STS | MAPK1 833/4885CYP3A4 3265/4885CTSC 1287/4885 |
| US-11447448-B2 | Process for the preparation of solriamfetol and salt thereof | TST, SPR, STS | MAPK1 833/4885CYP3A4 3265/4885CTSC 1287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.