Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.64 |
| ▸ | MAPT | P10636 | 8/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.64 |
| ▸ | MEN1 | O00255 | 7/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | WDR5 | P61964 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9621677 | 0.85 | MAPT (0.67) | ALDH1A1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL11321535 | 0.83 | SMN1; SMN2 (0.58) | ALDH1A1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL11315394 | 0.83 | POLB (0.55) | ALDH1A1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL11326282 | 0.83 | MYC (0.65) | ALDH1A1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL11456650 | 0.81 | PTGDR2 (0.49) | ALDH1A1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL11324014 | 0.79 | GAA (0.57) | ALDH1A1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL30818066 | 0.79 | MAPT (1.00) | ALDH1A1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL28819009 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL11321537 | 0.78 | MYC (0.51) | ALDH1A1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL11326245 | 0.78 | MYC (0.51) | ALDH1A1MAPTKMT2AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240066136-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI), INC. (CN) | 2024-02-29 | — | — | US | disclosed |
| EP-3442952-A1 | METHODS OF TREATMENT OF CHOLESTASIS AND FIBROSIS | Genfit (FR) | 2019-02-20 | — | — | EP | disclosed |
| WO-2017178174-A1 | METHODS OF TREATMENT OF CHOLESTASIS AND FIBROSIS | GENFIT (FR) | 2017-10-19 | — | — | WO | disclosed |
| US-20170290814-A1 | METHODS OF TREATMENT OF CHOLESTASIS AND FIBROSIS | GENFIT (FR) | 2017-10-12 | — | — | US | disclosed |
| US-4456668-A | DYE BLEACH, TEXTILE DYES | CIBA GEIGY AG (CH) | 1984-06-26 | — | — | US | disclosed |
| US-4409143-A | TEXTILES, PHOTOGRAPHY | CIBA-GEIGY AG (CH) | 1983-10-11 | — | — | US | disclosed |
| EP-0083009-A1 | Dispersion dyestuffs | BASF Aktiengesellschaft (DE) | 1983-07-06 | — | — | EP | disclosed |
| US-4313872-A | MONDAZO AND DISAZO DYES | CASSELLA AKTIENGESELLSCHAFT (DE) | 1982-02-02 | — | — | US | disclosed |
| EP-0040171-A2 | Azo dyestuffs, methods for their preparation and their use as colouring agents in the silver dyestuff bleaching process | CIBA-GEIGY AG (CH) | 1981-11-18 | — | — | EP | disclosed |
| US-4252530-A | USING A BASE AS DISCHARGE AGENT IN A DISCHARGE RESIST PASTE AND HEATING | CASSELLA AKTIENGESELLSCHAFT (DE) | 1981-02-24 | — | — | US | disclosed |
| US-4006127-A | Cationic diazacyanine dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170290814-A1 | METHODS OF TREATMENT OF CHOLESTASIS AND FIBROSIS | NR1H4, SLC10A1, MMP1 | ALDH1A1 748/4885MAPT 4417/4885KMT2A 4164/4885 |
| US-20240066136-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | DDB1, DCLRE1A, MDM2 | ALDH1A1 1427/4885MAPT 3010/4885KMT2A 1342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.