Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MPI | P34949 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11044416 | 0.76 | BRD4 (0.45) | CYP3A4MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL11043192 | 0.73 | ATM (0.37) | ATMCYP3A4MAPTALDH1A1LMNA | |
| SCHEMBL11038859 | 0.70 | BRD4 (0.39) | CYP3A4MAPTALDH1A1GAA | |
| SCHEMBL11160277 | 0.70 | GAA (0.45) | ATMCYP3A4MAPTALDH1A1LMNA | |
| SCHEMBL11041605 | 0.69 | BRD4 (0.39) | CYP3A4MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL11039921 | 0.67 | LMNA (0.43) | ATMCYP3A4MAPTLMNAKMT2A | |
| SCHEMBL11038869 | 0.67 | ATM (0.37) | ATMCYP3A4MAPTLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL11038861 | 0.66 | ATM (0.36) | ATMCYP3A4MAPTLMNATDP1 | |
| SCHEMBL11356640 | 0.63 | ATM (0.66) | ATMCYP3A4MAPTLMNAKMT2A | |
| SCHEMBL18535902 | 0.62 | MAPT (0.56) | ATMCYP3A4MAPTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116444-A2 | Improvements in or relating to benzazepine derivatives | ELI LILLY AND COMPANY (US) | 1984-08-22 | — | — | EP | disclosed |