Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11038861 | 0.98 | ATM (0.36) | ATMMAPTCYP3A4POLBKDM4E | |
| SCHEMBL11041640 | 0.76 | BRD4 (0.45) | MAPTCYP3A4KDM4EGAA | |
| SCHEMBL11043192 | 0.76 | ATM (0.37) | ATMMAPTCYP3A4POLBKDM4E | |
| SCHEMBL11039921 | 0.76 | LMNA (0.43) | ATMMAPTCYP3A4POLBKDM4E | |
| Hydrochloric Acid SCHEMBL11040043 | 0.75 | BRD4 (0.44) | MAPTCYP3A4POLBKDM4EGAA | |
| SCHEMBL11060113 | 0.74 | ADORA1 (0.31) | ADORA1ACHE | |
| Hydrochloric Acid SCHEMBL11056785 | 0.69 | ADRA1A (0.37) | MAPTCYP3A4KDM4EACHEGAA | |
| SCHEMBL11040367 | 0.69 | MAPT (0.40) | MAPTCYP3A4KDM4EGAALMNA | |
| SCHEMBL11057303 | 0.69 | MAPT (0.40) | MAPTCYP3A4KDM4EGAALMNA | |
| Hydrochloric Acid SCHEMBL11038881 | 0.69 | BRD4 (0.38) | MAPTCYP3A4POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115961-A2 | Process for preparing benzazepines | ELI LILLY AND COMPANY (US) | 1984-08-15 | — | — | EP | claimed |
| EP-0116444-A2 | Improvements in or relating to benzazepine derivatives | ELI LILLY AND COMPANY (US) | 1984-08-22 | — | — | EP | disclosed |