Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 13/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11040170 | 0.84 | BCHE (0.58) | ELANECYP2D6LMNAADRB2BCHE | |
| SCHEMBL11037438 | 0.81 | ELANE (0.53) | ELANEMAPTTDP1L3MBTL1PRTN3 | |
| SCHEMBL11036788 | 0.77 | ELANE (0.58) | ELANEMAPTTDP1L3MBTL1PRTN3 | |
| Sulfuric Acid SCHEMBL11062736 | 0.77 | BCHE (0.47) | ELANECYP2D6LMNAADRB2BCHE | |
| Sulfuric Acid SCHEMBL11040333 | 0.76 | ELANE (0.39) | ELANECYP2D6LMNAADRB2BCHE | |
| SCHEMBL11575276 | 0.74 | LMNA (0.64) | ELANECYP2D6LMNAADRB2BCHE | |
| SCHEMBL16300513 | 0.73 | ELANE (0.73) | ELANEALDH1A1MAPTTDP1L3MBTL1 | |
| Divabuterol SCHEMBL2109920 | 0.73 | BCHE (0.71) | CYP2D6LMNAADRB2BCHEACHE | |
| Hydrochloric Acid SCHEMBL11036696 | 0.73 | BCHE (0.59) | CYP2D6LMNAADRB2BCHEACHE | |
| Divabuterol SCHEMBL11702548 | 0.72 | BCHE (0.69) | CYP2D6LMNAADRB2BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046144-B1 | THERAPEUTICALLY ACTIVE DERIVATIVES OF PHENYLETHANOL AMINES | Aktiebolaget Draco (SE) | 1984-04-11 | — | — | EP | disclosed |
| US-4442300-A | BRONCHOSPASMOLYTIC | AKTIEBOLAGET DRACO (SE) | 1984-04-10 | — | — | US | disclosed |
| EP-0046144-A1 | Therapeutically active derivatives of phenylethanol amines | Aktiebolaget Draco (SE) | 1982-02-17 | — | — | EP | disclosed |