Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | NCF1 | P14598 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 4/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
| ▸ | HTR2B | P41595 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9638384 | 0.86 | ALDH1A1 (0.63) | ALDH1A1KDM4EHTTHPGDNCF1 | |
| SCHEMBL3583103 | 0.83 | HRH3 (0.73) | ALDH1A1KDM4EHTTHPGDHRH3 | |
| Hydrochloric Acid SCHEMBL3574408 | 0.82 | HRH3 (0.71) | ALDH1A1KDM4EHTTHPGDHRH3 | |
| SCHEMBL12124941 | 0.82 | ALDH1A1 (0.68) | ALDH1A1KDM4EHTTHPGDNCF1 | |
| SCHEMBL14432882 | 0.79 | KDM4E (0.71) | ALDH1A1KDM4EHTTHPGDNCF1 | |
| SCHEMBL13791587 | 0.79 | SIGMAR1 (0.72) | ALDH1A1KDM4EHTTHPGDNCF1 | |
| SCHEMBL10806904 | 0.78 | KDM4E (0.56) | ALDH1A1KDM4EHTTHPGDSMN1; SMN2 | |
| SCHEMBL7416950 | 0.78 | KDM4E (0.63) | ALDH1A1KDM4EHTTHPGDNCF1 | |
| SCHEMBL7416946 | 0.78 | KDM4E (0.63) | ALDH1A1KDM4EHTTHPGDNCF1 | |
| SCHEMBL10664787 | 0.78 | ALDH1A1 (0.52) | ALDH1A1KDM4EHTTHPGDHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0099121-A2 | Pharmaceutical compositions | Bristol-Myers Company (US) | 1984-01-25 | — | — | EP | disclosed |