Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | NCF1 | P14598 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7425223 | 0.84 | SIGMAR1 (0.52) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL12124941 | 0.82 | ALDH1A1 (0.68) | KDM4EALDH1A1HPGDHTTNCF1 | |
| SCHEMBL7416946 | 0.81 | KDM4E (0.63) | KDM4EALDH1A1HPGDHTTNCF1 | |
| SCHEMBL7422613 | 0.80 | ALDH1A1 (0.65) | KDM4EALDH1A1HPGDHTTNCF1 | |
| SCHEMBL13791587 | 0.79 | SIGMAR1 (0.72) | KDM4EALDH1A1HPGDHTTNCF1 | |
| SCHEMBL14432882 | 0.79 | KDM4E (0.71) | KDM4EALDH1A1HPGDHTTNCF1 | |
| SCHEMBL11040258 | 0.78 | ALDH1A1 (0.63) | KDM4EALDH1A1HPGDHTTNCF1 | |
| SCHEMBL9638384 | 0.78 | ALDH1A1 (0.63) | KDM4EALDH1A1HPGDHTTNCF1 | |
| SCHEMBL16741172 | 0.77 | SMN1; SMN2 (0.62) | ALDH1A1HPGDHTTHRH3MEN1 | |
| SCHEMBL17099378 | 0.77 | ALDH1A1 (1.00) | KDM4EALDH1A1HPGDHTTNCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013066-A1 | CYCLIC AMIDES OF 3-AMINO-2-HYDROXY-CARBOXYLIC ACIDS AS HIV-PROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1993-07-08 | — | — | WO | disclosed |