Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11502974 | 0.97 | GHSR (0.32) | PTGESGHSRHTT | |
| SCHEMBL11035846 | 0.95 | GHSR (0.34) | PTGESGHSR | |
| SCHEMBL11038602 | 0.90 | PTGES (0.36) | PTGES | |
| SCHEMBL11617589 | 0.84 | PTGES (0.40) | PTGESGHSRHTT | |
| SCHEMBL11615496 | 0.83 | GHSR (0.40) | PTGESGHSRHTT | |
| SCHEMBL11668152 | 0.82 | GHSR (0.41) | PTGESGHSR | |
| SCHEMBL11502663 | 0.79 | APP (0.32) | HTT | |
| SCHEMBL11502480 | 0.76 | HTT (0.31) | HTT | |
| SCHEMBL11502677 | 0.76 | HTT (0.31) | HTT | |
| SCHEMBL11502603 | 0.75 | HTT (0.30) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0043713-B1 | ANTIBACTERIAL CEPHALOSPORINS | SMITHKLINE BECKMAN CORPORATION (US) | 1984-09-26 | — | — | EP | disclosed |
| EP-0043713-A1 | Antibacterial cephalosporins | SMITHKLINE BECKMAN CORPORATION (US) | 1982-01-13 | — | — | EP | disclosed |
| US-4308267-A | 7-[2-Alkoxyimino-2-(amino-thiazole)acetamido]-3-[1-(sulfaminoalkly)tetrazolthiomethyl]cephalosporins | SMITHKLINE CORPORATION (US) | 1981-12-29 | — | — | US | disclosed |
| US-4178288-A | Sulfaminoalkyl substituted tetrazole thiol intermediates for preparing cephalosporins | SMITHKLINE CORPORATION (US) | 1979-12-11 | — | — | US | disclosed |
| US-4171362-A | 7-Acylamino-3-(sulfaminoalkyl substituted tetrazolylthiomethyl)cephalosporins antibacterial compositions containing them and methods of treating bacterial infections with them | SMITHKLINE CORPORATION (US) | 1979-10-16 | — | — | US | disclosed |
| US-4171368-A | 7-Acylamino-3-(sulfaminoalkyl substituted tetrazolylthiomethyl)cephalosporins, antibacterial compositions containing them and methods of treating bacterial infections with them | SMITHKLINE CORPORATION (US) | 1979-10-16 | — | — | US | disclosed |
| US-4171433-A | 7-Amino-3-(sulfaminoalkyl substituted tetrazolylthiomethyl)cephalosporin intermediates for preparing 7-acylamino cephalosporins | SMITHKLINE CORPORATION (US) | 1979-10-16 | — | — | US | disclosed |
| US-4118491-A | 7-Acyl-3-(sulfaminoalkyl substituted tetrazolylthiomethyl)cephalosporins, antibacterial compositions containing them and methods of treating bacterial infections with them | SMITHKLINE CORPORATION (US) | 1978-10-03 | — | — | US | disclosed |
| US-4066762-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1978-01-03 | — | — | US | disclosed |