Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11615496 | 0.98 | GHSR (0.40) | GHSRPTGESHSD17B10TDP1POLB | |
| SCHEMBL11617589 | 0.94 | PTGES (0.40) | GHSRPTGESHSD17B10POLBALDH1A1 | |
| SCHEMBL10607988 | 0.88 | PTGES (0.49) | GHSRPTGESHSD17B10POLB | |
| SCHEMBL11035846 | 0.87 | GHSR (0.34) | GHSRPTGES | |
| SCHEMBL11615205 | 0.86 | PTGES (0.48) | GHSRPTGESHSD17B10 | |
| SCHEMBL11502974 | 0.85 | GHSR (0.32) | GHSRPTGES | |
| SCHEMBL11040307 | 0.82 | PTGES (0.33) | GHSRPTGES | |
| SCHEMBL11502480 | 0.77 | HTT (0.31) | — | |
| SCHEMBL11502677 | 0.77 | HTT (0.31) | — | |
| SCHEMBL11038602 | 0.75 | PTGES (0.36) | PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4101656-A | 7β-Acylamino-3-(alkanesulfonamidoalkyl substituted tetrazolylthiomethyl) cephalosporins, antibacterial compositions containing them and methods of treating bacterial infections with them | SMITHKLINE CORPORATION (US) | 1978-07-18 | — | — | US | disclosed |