Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 6/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10481812 | 0.92 | ADORA1 (0.37) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL735544 | 0.85 | ADORA3 (0.39) | ADORA1ADORA3ADORA2AADORA2BLMNA | |
| SCHEMBL28249867 | 0.82 | ADORA3 (0.49) | ADORA1ADORA3ADORA2AADORA2BSMN1; SMN2 | |
| SCHEMBL10481813 | 0.80 | ADORA1 (0.39) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL9773301 | 0.79 | ADORA2A (0.36) | ADORA1ADORA3ADORA2AADORA2BTSHR | |
| SCHEMBL30301920 | 0.78 | BTK (0.35) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL7061902 | 0.78 | ADORA2A (0.43) | ADORA1ADORA3ADORA2AADORA2BSMN1; SMN2 | |
| SCHEMBL28165438 | 0.77 | ADORA1 (0.45) | ADORA1ADORA3ADORA2AADORA2BLMNA | |
| SCHEMBL29834195 | 0.76 | ADORA1 (0.41) | ADORA1 | |
| SCHEMBL27518665 | 0.76 | ADORA1 (0.43) | ADORA1ADORA3ADORA2AADORA2BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0102995-A1 | POLYNUCLEOTIDE SYNTHESIS | CELLTECH LIMITED (GB) | 1984-03-21 | — | — | EP | disclosed |
| WO-1983003098-A1 | POLYNUCLEOTIDE SYNTHESIS | EATON, MICHAEL, ANTHONY, WILLIAM | 1983-09-15 | — | — | WO | disclosed |