SCHEMBL11040986

SCHEMBL11040986

CC1(Br)CC1(c1ccccc1)c1ccccc1.[MgH2]

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
OPRM1 P35372 1/20 0.38
OPRK1 P41145 1/20 0.38
OPRL1 P41146 1/20 0.38
LMNA P02545 2/20 0.35
ALDH1A1 P00352 1/20 0.35
GAA P10253 1/20 0.35
PAX8 Q06710 1/20 0.35
MCL1 Q07820 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
MMP2 P08253 1/20 0.34
MMP9 P14780 1/20 0.34
GRIN2B Q13224 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TSHR P16473 1/20 0.33
ALOX12 P18054 1/20 0.33
ACHE P22303 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5078420 0.98 MEN1 (0.46) MEN1KMT2AOPRM1OPRK1OPRL1
SCHEMBL5076533 0.77 MEN1 (0.39) MEN1KMT2AOPRM1OPRK1OPRL1
SCHEMBL3310454 0.73 MEN1 (0.46) MEN1KMT2AOPRM1OPRK1OPRL1
SCHEMBL9541911 0.73 MEN1 (0.46) MEN1KMT2AMAOAMAOBGRIN2B
SCHEMBL2354190 0.73 LMNA (0.41) MEN1KMT2AOPRM1OPRK1OPRL1
SCHEMBL5080028 0.73 MEN1 (0.46) MEN1KMT2AOPRM1OPRK1OPRL1
SCHEMBL10895446 0.73 MEN1 (0.42) MEN1KMT2AOPRM1OPRK1OPRL1
SCHEMBL23532475 0.71 MEN1 (0.37) MEN1KMT2AOPRM1OPRK1OPRL1
SCHEMBL11064099 0.69 ALDH1A1 (0.46) MEN1KMT2AOPRM1OPRK1OPRL1
SCHEMBL11064104 0.69 ALDH1A1 (0.46) MEN1KMT2AOPRM1OPRK1OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0103120-A2 Process for producing a catalyst component used for the polymerization of alpha-olefins TOYO STAUFFER CHEMICAL CO. LTD. (JP) 1984-03-21 EP disclosed