Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 5/20 | 0.39 |
| ▸ | MAOA | P21397 | 4/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11064104 | 1.00 | ALDH1A1 (0.46) | ALDH1A1LMNAGAAPAX8MCL1 | |
| SCHEMBL30312220 | 0.82 | OPRM1 (0.50) | ALDH1A1LMNAGAAPAX8MCL1 | |
| SCHEMBL9655266 | 0.81 | MAOB (0.45) | ALDH1A1LMNAGAAPAX8MCL1 | |
| SCHEMBL1641588 | 0.81 | RAB9A (0.45) | ALDH1A1LMNAGAAPAX8MCL1 | |
| SCHEMBL15778080 | 0.81 | MAOA (0.45) | ALDH1A1LMNAGAAPAX8MCL1 | |
| SCHEMBL2354190 | 0.81 | LMNA (0.41) | ALDH1A1LMNAGAAPAX8MCL1 | |
| Hydrochloric Acid SCHEMBL15777055 | 0.79 | MAOA (0.43) | MAOBMAOAPNMT | |
| SCHEMBL6439973 | 0.77 | OPRL1 (0.44) | ALDH1A1LMNAGAAPAX8MCL1 | |
| SCHEMBL6439975 | 0.77 | OPRL1 (0.44) | ALDH1A1LMNAGAAPAX8MCL1 | |
| SCHEMBL5080028 | 0.76 | MEN1 (0.46) | ALDH1A1LMNAGAAPAX8MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4442119-A | Cyclopropyl analogs as estrogenic and anti-fertility agents | THE BOARD OF REGENTS FOR THE UNIVERSITY OF OKLAHOMA (US) | 1984-04-10 | — | — | US | disclosed |