Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.60 |
| ▸ | BCL2 | P10415 | 2/20 | 0.51 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.51 |
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23576323 | 0.87 | ACACB (0.50) | P4HTMALPLACACBKDM4EALDH1A1 | |
| SCHEMBL1403507 | 0.86 | P4HTM (0.63) | P4HTMBCL2MDM2MCL1PLA2G4B | |
| SCHEMBL9733601 | 0.84 | RARB (0.68) | PLA2G4BKDM4EALDH1A1LMNAL3MBTL1 | |
| SCHEMBL13731115 | 0.80 | P4HTM (0.64) | P4HTMKDM4EALDH1A1LMNAL3MBTL1 | |
| SCHEMBL9613265 | 0.80 | ALDH1A1 (0.57) | P4HTMALPLRXRARXRBKDM4E | |
| SCHEMBL2633139 | 0.78 | EGLN1 (0.62) | P4HTMMCL1KDM4EALDH1A1LMNA | |
| SCHEMBL202683 | 0.78 | PLA2G4B (0.74) | PLA2G4BRXRARXRBTSHRNPC1 | |
| SCHEMBL12254177 | 0.77 | HIF1A (0.62) | P4HTMMCL1KDM4EALDH1A1LMNA | |
| SCHEMBL71034 | 0.77 | HIF1A (0.55) | P4HTMKDM4EALDH1A1LMNAL3MBTL1 | |
| SCHEMBL29929320 | 0.77 | HIF1A (0.55) | P4HTMKDM4EALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1984004302-A1 | SUBSTITUTED PICOLINIC ACIDS, PROCESSES FOR THEIR PREPARATION, THEIR USE AND MEDICAMENTS CONTAINING THEM | BYK GULDEN LOMBERG CHEM FAB (DE) | 1984-11-08 | — | — | WO | disclosed |