Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | THPO | P40225 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | P4HTM | Q9NXG6 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12254177 | 0.87 | HIF1A (0.62) | ALDH1A1KDM4EL3MBTL1HIF1AMEN1 | |
| SCHEMBL23512615 | 0.86 | EGLN1 (0.44) | ALDH1A1KDM4EL3MBTL1HIF1AMEN1 | |
| SCHEMBL286868 | 0.85 | KDM4E (0.69) | ALDH1A1KDM4EL3MBTL1HIF1AMEN1 | |
| SCHEMBL13731115 | 0.83 | P4HTM (0.64) | ALDH1A1KDM4EL3MBTL1HIF1AMEN1 | |
| SCHEMBL31215931 | 0.83 | BCL2 (0.61) | ALDH1A1KDM4EL3MBTL1HIF1AMEN1 | |
| SCHEMBL10622984 | 0.83 | ALDH1A1 (0.70) | ALDH1A1KDM4EL3MBTL1HIF1AMEN1 | |
| SCHEMBL16726559 | 0.83 | P4HTM (0.74) | ALDH1A1KDM4EL3MBTL1HIF1AMEN1 | |
| SCHEMBL17810013 | 0.82 | PLK1 (0.53) | HIF1ARAB9ANPC1EGLN1 | |
| SCHEMBL9734065 | 0.82 | ALDH1A1 (0.68) | ALDH1A1KDM4EL3MBTL1HIF1AMEN1 | |
| SCHEMBL2633139 | 0.80 | EGLN1 (0.62) | ALDH1A1KDM4EL3MBTL1HIF1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1727797-B1 | PROCESS FOR CROSS COUPLING INDOLES | BOEHRINGER INGELHEIM PHARMA (US) | 2012-05-30 | — | — | EP | disclosed |
| EP-1414797-B1 | HEPATITIS C VIRUS POLYMERASE INHIBITORS WITH A HETEROBICYLIC STRUCTURE | BOEHRINGER INGELHEIM CA LTD (CA) | 2008-01-02 | — | — | EP | disclosed |