SCHEMBL1104100

SCHEMBL1104100

C=C(C)COOCC(C)(CC)C(=O)OCC

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PKM P14618 3/20 0.33
KDM4E B2RXH2 1/20 0.33
CYP4F2 P78329 2/20 0.33
CYP4A11 Q02928 2/20 0.33
THRB P10828 1/20 0.33
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32
HTT P42858 1/20 0.32
MMP8 P22894 1/20 0.31
MAPT P10636 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1104137 0.87 THRB (0.34) CYP4F2CYP4A11THRBALDH1A1
SCHEMBL1104115 0.87
SCHEMBL14369211 0.84 CYP4F2 (0.36) PKMCYP4F2CYP4A11THRBHTT
SCHEMBL14369212 0.81 ACHE (0.31)
SCHEMBL12793116 0.77 THRB (0.44) PKMKDM4ECYP4F2CYP4A11THRB
SCHEMBL9247480 0.75 ALDH1A1 (0.50) PKMKDM4ECYP4F2CYP4A11THRB
SCHEMBL6383219 0.74 ALDH1A1 (0.46) PKMKDM4ECYP4F2CYP4A11THRB
SCHEMBL12330362 0.73 ALDH1A1 (0.41) PKMKDM4ECYP4F2CYP4A11THRB
SCHEMBL13546036 0.73 CYP4F2 (0.39) PKMKDM4ECYP4F2CYP4A11THRB
SCHEMBL1104093 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8151705-B2 Method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-7883827-B2 acrylate copolymer binder has superior developing properties while suppressing damages resulting from permeation of the developer caused by the acid content; for use with a laser beam; excellent in printing durability and image formation FUJIFILM CORPORATION (JP) 2011-02-08 US disclosed
US-20100081771-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed
US-7507525-B2 Polymerizable composition and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2009-03-24 US disclosed
US-7338748-B2 Polymerizable composition and planographic printing plate precursor FUJIFILM CORPORATION (JP) 2008-03-04 US disclosed
US-7279539-B2 Alkali-soluble polymer and polymerizable composition thereof FUJIFILM CORPORATION (JP) 2007-10-09 US disclosed
US-20070202439-A1 Polymerizable composition and planographic printing plate precursor FUJIFILM CORPORATION 2007-08-30 US disclosed