Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6352266 | 0.89 | SLC6A3 (0.47) | GAASLC6A3ALDH1A1SLC6A4LMNA | |
| SCHEMBL3443527 | 0.83 | SLC6A3 (0.49) | GAAHPGDSLC6A3ALDH1A1SLC6A4 | |
| SCHEMBL3521066 | 0.82 | SLC6A3 (0.55) | GAASLC6A3ALDH1A1SLC6A4LMNA | |
| SCHEMBL9486496 | 0.79 | SLC6A3 (0.42) | GAASLC6A3ALDH1A1SLC6A4LMNA | |
| SCHEMBL613620 | 0.78 | GAA (0.50) | GAAHPGDSLC6A3ALDH1A1SLC6A4 | |
| SCHEMBL10052501 | 0.77 | OPRM1 (0.57) | SLC6A3SLC6A4 | |
| SCHEMBL3934115 | 0.75 | SLC6A3 (0.48) | GAAHPGDSLC6A3ALDH1A1SLC6A4 | |
| Hydrochloric Acid SCHEMBL4257944 | 0.74 | SLC6A3 (0.47) | GAAHPGDSLC6A3ALDH1A1SLC6A4 | |
| SCHEMBL1558011 | 0.74 | ALDH1A1 (0.38) | ALDH1A1LMNA | |
| SCHEMBL735822 | 0.73 | OPRM1 (0.47) | GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0035902-B1 | 1-(4-ARYL-CYCLOHEXYL)PIPERIDINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1984-10-31 | — | — | EP | disclosed |
| US-4329353-A | ANTIEMETIC AND NEUROLEPTIC AGENTS | JANSSEN PHARMACEUTICA, N.V. (BE) | 1982-05-11 | — | — | US | disclosed |