Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10397861 | 0.88 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1HPGDPOLBKDM4E | |
| SCHEMBL950942 | 0.87 | POLB (0.62) | SMN1; SMN2ALDH1A1HPGDPOLBKDM4E | |
| SCHEMBL436967 | 0.86 | ALDH1A1 (0.59) | ALDH1A1HPGDPOLBL3MBTL1CYP2C9 | |
| SCHEMBL11780327 | 0.85 | POLB (0.65) | SMN1; SMN2ALDH1A1HPGDPOLBKDM4E | |
| SCHEMBL22426668 | 0.84 | NR4A2 (0.46) | SMN1; SMN2ALDH1A1HPGDPOLBKDM4E | |
| SCHEMBL9168588 | 0.84 | ALDH1A1 (0.57) | ALDH1A1HPGDPOLBL3MBTL1CYP2C9 | |
| SCHEMBL11111854 | 0.82 | POLB (0.47) | SMN1; SMN2ALDH1A1HPGDPOLBKDM4E | |
| SCHEMBL14854015 | 0.81 | PDK1 (0.44) | SMN1; SMN2ALDH1A1HPGDPOLBKDM4E | |
| SCHEMBL11040582 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1POLBCYP2C9CYP2C19 | |
| SCHEMBL11754600 | 0.81 | MAPT (0.50) | SMN1; SMN2ALDH1A1POLBCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7867949-B2 | Hydrazide compound and pesticidal use of the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-01-11 | — | — | US | disclosed |
| US-20090181956-A1 | Hydrazide Compound and Pesticidal Use of the Same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-07-16 | — | — | US | disclosed |
| US-4465502-A | Herbicidal N-haloacetyl-2-substituted-6-acylanilines | CHEVRON RESEARCH COMPANY (US) | 1984-08-14 | — | — | US | disclosed |
| US-4456471-A | PREEMERGENCE HERBICIDE FOR GRASSES | CHEVRON RESEARCH COMPANY (US) | 1984-06-26 | — | — | US | disclosed |
| US-4348222-A | Herbicidal N-haloacetyl-2-alkyl-6-acylanilines | CHEVRON RESEARCH COMPANY (US) | 1982-09-07 | — | — | US | disclosed |
| US-4244730-A | Herbicidal N-haloacetyl-2-alkyl-6-acylanilines | CHEVRON RESEARCH COMPANY (US) | 1981-01-13 | — | — | US | disclosed |
| US-4032573-A | ANESTHETIC, ANTIARRYTHMIA | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181956-A1 | Hydrazide Compound and Pesticidal Use of the Same | ACHE, DDT, CAT | SMN1; SMN2 2755/4885ALDH1A1 436/4885HPGD 358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.