Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | MAOA | P21397 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | HCN4 | Q9Y3Q4 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11039717 | 0.86 | BRD4 (0.41) | BRD4CYP3A4MAPTKDM4EMAOA | |
| SCHEMBL11041640 | 0.81 | BRD4 (0.45) | BRD4CYP3A4MAPTKDM4EMAOA | |
| Hydrochloric Acid SCHEMBL11040043 | 0.80 | BRD4 (0.44) | BRD4CYP3A4MAPTKDM4EMAOA | |
| SCHEMBL11054742 | 0.79 | BRD4 (0.43) | BRD4CYP3A4MAPTKDM4EMAOA | |
| SCHEMBL11719093 | 0.78 | BRD4 (0.42) | BRD4CYP3A4MAPTKDM4EMAOA | |
| SCHEMBL11063789 | 0.75 | BRD4 (0.40) | BRD4CYP3A4MAPTKDM4EMAOA | |
| SCHEMBL1533850 | 0.75 | BRD4 (0.53) | BRD4CYP3A4MAPTKDM4EMAOA | |
| Hydrochloric Acid SCHEMBL11055170 | 0.74 | BRD4 (0.40) | BRD4CYP3A4MAPTKDM4EMAOA | |
| SCHEMBL11057303 | 0.73 | MAPT (0.40) | BRD4CYP3A4MAPTKDM4EALDH1A1 | |
| SCHEMBL11040367 | 0.73 | MAPT (0.40) | BRD4CYP3A4MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116444-A2 | Improvements in or relating to benzazepine derivatives | ELI LILLY AND COMPANY (US) | 1984-08-22 | — | — | EP | disclosed |