Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HSD17B3 | P37058 | 3/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30089549 | 0.87 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2AATMPLK1 | |
| SCHEMBL27818298 | 0.83 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2AATMPLK1 | |
| SCHEMBL27447196 | 0.83 | HSD17B3 (0.67) | ALDH1A1KMT2ASMN1; SMN2HPGDNPC1 | |
| SCHEMBL5270771 | 0.83 | HSD17B3 (0.67) | ALDH1A1MEN1KMT2AATMPLK1 | |
| SCHEMBL27352122 | 0.82 | THRA (0.62) | ALDH1A1MEN1KMT2APLK1HPGD | |
| SCHEMBL10017467 | 0.82 | L3MBTL1 (0.59) | ALDH1A1MEN1KMT2AATMPLK1 | |
| SCHEMBL5866548 | 0.80 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2AATMPLK1 | |
| SCHEMBL10792717 | 0.80 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2AATMPLK1 | |
| SCHEMBL11705272 | 0.80 | THRA (0.65) | ALDH1A1MEN1KMT2AATMPLK1 | |
| SCHEMBL5081078 | 0.80 | L3MBTL1 (0.73) | ALDH1A1MEN1KMT2AATMPLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1040876-C | New derivatives of erythromycin, their preparation process, their use as medicaments | ROUSSEL UCLAF (FR) | 1998-11-25 | — | — | CN | disclosed |
| CN-1090581-A | The preparation method of the novel derivative of erythromycin and they and as the application of medicine | ROUSSEL UCLAF (FR) | 1994-08-10 | — | — | CN | disclosed |
| US-4487772-A | CARDIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO. LTD. (JP) | 1984-12-11 | — | — | US | disclosed |
| US-4468402-A | Carbostyril derivatives, process for producing the same and cardiotonic compositions containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4454130-A | CARDIOTONIC, HYPOTENSIVE AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-12 | — | — | US | disclosed |
| US-4141893-A | Decahydrocyclopent[c]azepines | ELI LILLY AND COMPANY (US) | 1979-02-27 | — | — | US | disclosed |