Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10830423 | 0.88 | HTR3E (0.38) | PDE2AHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL8462010 | 0.82 | HTR3E (0.41) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7921991 | 0.80 | CYP11B1 (0.41) | PDE2AHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL9628313 | 0.78 | KIF11 (0.36) | PDE2AHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL668872 | 0.78 | PDE2A (0.41) | PDE2APLAU | |
| SCHEMBL30792979 | 0.76 | KIF11 (0.35) | PDE2AHTR3EHTR3BHTR3AHTR3D | |
| Fluoride Ion SCHEMBL10713269 | 0.73 | PDE2A (0.38) | PDE2APLAU | |
| SCHEMBL7272204 | 0.73 | NOTUM (0.42) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL1531168 | 0.72 | PDE2A (0.37) | PDE2APLAU | |
| SCHEMBL8975023 | 0.71 | HTR3E (0.42) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4469893-A | Method for the preparation of nitrodiphenyl ethers | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-09-04 | — | — | US | disclosed |