Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.40 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.40 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride Ion SCHEMBL10713269 | 0.95 | PDE2A (0.38) | PDE2AALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL1531168 | 0.87 | PDE2A (0.37) | PDE2AALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL10262533 | 0.85 | PDE2A (0.40) | PDE2AALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL30530057 | 0.84 | PDE2A (0.39) | PDE2AALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL10680627 | 0.84 | GABRB3 (0.36) | PDE2AALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL9339616 | 0.84 | PTPN5 (0.41) | PDE2AALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL9339574 | 0.84 | ALDH1A1 (0.38) | PDE2AALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL2331553 | 0.84 | PDE2A (0.39) | PDE2AALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL26617143 | 0.84 | PDE2A (0.35) | PDE2AALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL17062134 | 0.80 | PKM (0.38) | PDE2AALDH1A1CYP3A4HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100096585-A1 | Process for Preparing 2,6-Dichloro-4-(Trifluoromethyl)Phenylhydrazine Using Mixtures of Dichloro-Fluoro-Trifluoromethylbenzenes | BASF SE (DE) | 2010-04-22 | — | — | US | claimed |
| EP-0180057-B1 | PROCESS FOR THE PREPARATION OF HALO AROMATIC COMPOUNDS | OCCIDENTAL CHEMICAL CORPORATION (US) | 1989-08-09 | — | — | EP | claimed |
| EP-0289036-A1 | Preparation of 3-chloro-4,5-difluorobenzotrifluoride | OCCIDENTAL CHEMICAL CORPORATION (US) | 1988-11-02 | — | — | EP | claimed |
| US-4603222-A | Method for the preparation of nitrodiphenyl ethers | OCCIDENTAL CHEMICAL CORPORATION (US) | 1986-07-29 | — | — | US | claimed |
| EP-0180057-A1 | Process for the preparation of halo aromatic compounds | OCCIDENTAL CHEMICAL CORPORATION (US) | 1986-05-07 | — | — | EP | claimed |
| EP-0173349-A1 | Method for the preparation of nitrodiphenyl ethers | OCCIDENTAL CHEMICAL CORPORATION (US) | 1986-03-05 | — | — | EP | claimed |
| EP-0159388-A2 | Preparation of nuclear chlorinated compounds | OCCIDENTAL CHEMICAL CORPORATION (US) | 1985-10-30 | — | — | EP | claimed |
| EP-4709712-A1 | GSK3A INHIBITORS AND METHODS OF USE THEREOF | Blueprint Medicines Corporation (US) | 2026-03-18 | — | — | EP | disclosed |
| CN-118978698-B | Hydrophobic thermoplastic polyimide resin and preparation method thereof | 江苏集萃功能材料研究所有限公司 | 2025-02-07 | — | — | CN | disclosed |
| CN-118978698-A | Hydrophobic thermoplastic polyimide resin and preparation method thereof | 江苏集萃功能材料研究所有限公司 | 2024-11-19 | — | — | CN | disclosed |
| WO-2024233900-A1 | GSK3A INHIBITORS AND METHODS OF USE THEREOF | BLUEPRINT MEDICINES CORPORATION (US) | 2024-11-14 | — | — | WO | disclosed |
| EP-1601642-B1 | BIOAVAILABLE DIACYLHYDRAZINE LIGANDS FOR MODULATING THE EXPRESSION OF EXOGENOUS GENES VIA AN ECDYSONE RECEPTOR COMPLEX | INTREXON CORP (US) | 2017-01-04 | — | — | EP | disclosed |
| EP-1601642-B1 | BIOAVAILABLE DIACYLHYDRAZINE LIGANDS FOR MODULATING THE EXPRESSION OF EXOGENOUS GENES VIA AN ECDYSONE RECEPTOR COMPLEX | INTREXON CORP (US) | 2017-01-04 | — | — | EP | disclosed |
| US-4469893-A | Method for the preparation of nitrodiphenyl ethers | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-09-04 | — | — | US | disclosed |
| EP-0034402-B1 | METHOD OF PREPARING FLUORINE-SUBSTITUTED DIPHENYL ETHER DERIVATIVES AND FLUORINE-SUBSTITUTED HALOGENO BENZENE DERIVATIVES FOR USE THEREIN | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-08-29 | — | — | EP | disclosed |
| US-4388472-A | Substituted diphenyl ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-06-14 | — | — | US | disclosed |
| US-4384135-A | REACTING A SUBSTITUTED BENZOTRIFLUORIDE WITH A SUBSTITUTED PHENOL | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1983-05-17 | — | — | US | disclosed |
| EP-0023100-B1 | HERBICIDAL COMPOSITIONS COMPRISING A DIPHENYL ETHER COMPOUND IN ADMIXTURE WITH ANOTHER HERBICIDE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-11-10 | — | — | EP | disclosed |
| EP-0034402-A2 | Method of preparing fluorine-substituted diphenyl ether derivatives and fluorine-substituted halogeno benzene derivatives for use therein | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-08-26 | — | — | EP | disclosed |
| EP-0023100-A1 | Herbicidal compositions comprising a diphenyl ether compound in admixture with another herbicide | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-01-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100096585-A1 | Process for Preparing 2,6-Dichloro-4-(Trifluoromethyl)Phenylhydrazine Using Mixtures of Dichloro-Fluoro-Trifluoromethylbenzenes | DAZAP1, CYP4Z1, CYP2F1 | PDE2A 3241/4885ALDH1A1 93/4885CYP3A4 41/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.