Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.50 |
| ▸ | MC4R | P32245 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 4/20 | 0.49 |
| ▸ | DRD3 | P35462 | 3/20 | 0.49 |
| ▸ | DRD4 | P21917 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8799177 | 0.86 | SIGMAR1 (0.52) | SIGMAR1NPC1TP53RAB9AHPGD | |
| SCHEMBL24514671 | 0.85 | NPC1 (0.71) | SIGMAR1NPC1TP53RAB9AHPGD | |
| SCHEMBL22793926 | 0.85 | NPC1 (0.71) | SIGMAR1NPC1TP53RAB9AHPGD | |
| SCHEMBL25108942 | 0.85 | NPC1 (0.71) | SIGMAR1NPC1TP53RAB9AHPGD | |
| Ammonia Solution, Strong SCHEMBL10911900 | 0.85 | DRD2 (0.62) | SIGMAR1NPC1TP53RAB9AHPGD | |
| SCHEMBL25110207 | 0.82 | NPC1 (0.53) | SIGMAR1NPC1TP53RAB9AHPGD | |
| SCHEMBL25111269 | 0.82 | NPC1 (0.53) | SIGMAR1NPC1TP53RAB9AHPGD | |
| SCHEMBL25481377 | 0.82 | NPC1 (0.53) | SIGMAR1NPC1TP53RAB9AHPGD | |
| SCHEMBL14076364 | 0.80 | SIGMAR1 (0.79) | SIGMAR1MEN1KMT2AHRH3MC4R | |
| SCHEMBL7425219 | 0.78 | SIGMAR1 (0.52) | SIGMAR1NPC1TP53RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0099121-A2 | Pharmaceutical compositions | Bristol-Myers Company (US) | 1984-01-25 | — | — | EP | disclosed |