Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | MC4R | P32245 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | CHKA | P35790 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416946 | 0.84 | KDM4E (0.63) | SIGMAR1ALDH1A1KDM4EACHEGAA | |
| SCHEMBL7425223 | 0.81 | SIGMAR1 (0.52) | SIGMAR1MC4RALDH1A1KDM4ETDP1 | |
| SCHEMBL7416094 | 0.80 | ITGB3 (0.62) | SIGMAR1MC4RALDH1A1KDM4ETDP1 | |
| SCHEMBL14076364 | 0.80 | SIGMAR1 (0.79) | SIGMAR1MC4RALDH1A1KDM4EGAA | |
| Ammonia Solution, Strong SCHEMBL10911900 | 0.80 | DRD2 (0.62) | SIGMAR1MC4RALDH1A1KDM4ETDP1 | |
| SCHEMBL11041528 | 0.78 | SIGMAR1 (0.52) | SIGMAR1MC4RALDH1A1KDM4ETDP1 | |
| SCHEMBL8799177 | 0.78 | SIGMAR1 (0.52) | SIGMAR1MC4RALDH1A1KDM4ETDP1 | |
| SCHEMBL25108942 | 0.77 | NPC1 (0.71) | SIGMAR1ALDH1A1KDM4ETDP1NPC1 | |
| SCHEMBL22793926 | 0.77 | NPC1 (0.71) | SIGMAR1ALDH1A1KDM4ETDP1NPC1 | |
| SCHEMBL24514671 | 0.77 | NPC1 (0.71) | SIGMAR1ALDH1A1KDM4ETDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013066-A1 | CYCLIC AMIDES OF 3-AMINO-2-HYDROXY-CARBOXYLIC ACIDS AS HIV-PROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1993-07-08 | — | — | WO | disclosed |