SCHEMBL11041589

SCHEMBL11041589

O=C(CC(=O)Nc1cc(Cl)c(Cl)cc1[N+](=O)[O-])Nc1cc(Cl)c(Cl)cc1[N+](=O)[O-]

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.56
KMT2A Q03164 5/20 0.56
POLB P06746 1/20 0.46
RECQL P46063 1/20 0.46
PKM P14618 1/20 0.45
MAPT P10636 3/20 0.45
LMNA P02545 1/20 0.45
HTT P42858 1/20 0.45
ALDH1A1 P00352 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
MAPK1 P28482 1/20 0.44
TP53 P04637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5316948 0.91 MEN1 (0.46) MEN1KMT2ARECQLPKMMAPT
SCHEMBL14530921 0.86 KMT2A (0.42) MEN1KMT2ARECQLPKMMAPT
SCHEMBL8697889 0.85 GAA (0.45) MEN1KMT2ARECQLPKMLMNA
SCHEMBL8692388 0.84 KMT2A (0.67) MEN1KMT2APOLBMAPTLMNA
SCHEMBL6609242 0.84 MEN1 (0.47) MEN1KMT2AMAPTLMNAHTT
SCHEMBL11460373 0.83 CXCR2 (0.46) MEN1KMT2AMAPTLMNAHTT
SCHEMBL8513944 0.83 MAPT (0.55) MEN1KMT2APOLBPKMMAPT
SCHEMBL8697182 0.82 L3MBTL1 (0.60) MEN1KMT2APOLBPKMMAPT
SCHEMBL9365098 0.81 RECQL (0.45) MEN1KMT2APOLBRECQLPKM
SCHEMBL6841979 0.79 ALDH1A1 (0.43) MEN1KMT2ARECQLPKMMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4490463-A SENSITIZERS EASTMAN KODAK COMPANY (US) 1984-12-25 US disclosed
EP-0121326-A2 Alkanediyl bridged benzimidazolo monomethine cyanine dyes, processes for their preparation, and photographic emulsions and elements containing such dyes EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1984-10-10 EP disclosed