SCHEMBL1104161

SCHEMBL1104161

CCC(C)(C)C(=O)Nc1ccc(C(C)(C)Br)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.59
HTT P42858 2/20 0.59
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
TDP1 Q9NUW8 1/20 0.53
L3MBTL1 Q9Y468 2/20 0.52
BRD4 O60885 1/20 0.49
PDK1 Q15118 1/20 0.46
PDK2 Q15119 1/20 0.46
PDK3 Q15120 1/20 0.46
PDK4 Q16654 1/20 0.46
HDAC1 Q13547 3/20 0.46
POLB P06746 1/20 0.45
CNR2 P34972 2/20 0.44
RIPK1 Q13546 2/20 0.44
HDAC3 O15379 2/20 0.43
HDAC4 P56524 2/20 0.43
HDAC7 Q8WUI4 2/20 0.43
HDAC2 Q92769 2/20 0.43
HDAC10 Q969S8 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12226380 0.91 L3MBTL1 (0.61) LMNAHTTMEN1KMT2ATDP1
SCHEMBL13296170 0.86 MEN1 (0.54) LMNAHTTMEN1KMT2ATDP1
SCHEMBL12226381 0.85 L3MBTL1 (0.73) LMNAHTTMEN1KMT2ATDP1
SCHEMBL13934889 0.84 POLB (0.55) LMNAHTTMEN1KMT2ATDP1
SCHEMBL97686 0.84 MEN1 (0.54) LMNAHTTMEN1KMT2ATDP1
SCHEMBL12863546 0.83 HDAC1 (0.55) LMNAHTTMEN1KMT2ATDP1
SCHEMBL13134415 0.82 MDM2 (0.52) LMNAHTTMEN1KMT2ATDP1
SCHEMBL13706549 0.82 MEN1 (0.53) LMNAHTTMEN1KMT2ATDP1
SCHEMBL19621272 0.82 MEN1 (0.53) LMNAHTTMEN1KMT2ATDP1
SCHEMBL10075598 0.82 MEN1 (0.53) LMNAHTTMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8151705-B2 Method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-7883827-B2 acrylate copolymer binder has superior developing properties while suppressing damages resulting from permeation of the developer caused by the acid content; for use with a laser beam; excellent in printing durability and image formation FUJIFILM CORPORATION (JP) 2011-02-08 US disclosed
US-20100081771-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed
US-7338748-B2 Polymerizable composition and planographic printing plate precursor FUJIFILM CORPORATION (JP) 2008-03-04 US disclosed
US-20070202439-A1 Polymerizable composition and planographic printing plate precursor FUJIFILM CORPORATION 2007-08-30 US disclosed