SCHEMBL1104169

SCHEMBL1104169

CCC(C)(C)C(=O)Nc1ccc(OC)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK1 Q15118 1/20 0.60
PDK2 Q15119 1/20 0.60
PDK3 Q15120 1/20 0.60
PDK4 Q16654 1/20 0.60
SMN1; SMN2 Q16637 4/20 0.58
NPC1 O15118 3/20 0.58
RAB9A P51151 2/20 0.58
KMT2A Q03164 5/20 0.56
MEN1 O00255 4/20 0.56
L3MBTL1 Q9Y468 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
TP53 P04637 1/20 0.53
ALOX15 P16050 1/20 0.53
SAE1 Q9UBE0 1/20 0.53
UBA2 Q9UBT2 1/20 0.53
ALDH1A1 P00352 4/20 0.53
PKM P14618 1/20 0.53
HTT P42858 1/20 0.51
MAPT P10636 2/20 0.51
KDM4E B2RXH2 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19884361 0.88 PDK1 (0.55) PDK1PDK2PDK3PDK4SMN1; SMN2
SCHEMBL12226380 0.88 L3MBTL1 (0.61) KMT2AMEN1L3MBTL1TDP1ALDH1A1
SCHEMBL10064131 0.85 KMT2A (0.49) PDK1PDK2PDK3PDK4KMT2A
SCHEMBL10345182 0.85 PDK1 (0.59) PDK1PDK2PDK3PDK4SMN1; SMN2
SCHEMBL16312853 0.85 PDK1 (0.59) PDK1PDK2PDK3PDK4SMN1; SMN2
SCHEMBL14582701 0.84 GAA (0.51) PDK1PDK2PDK3PDK4SMN1; SMN2
SCHEMBL12227098 0.83 MEN1 (0.76) PDK1PDK2PDK3PDK4KMT2A
SCHEMBL1104156 0.83 KMT2A (0.47) PDK1PDK2PDK3PDK4KMT2A
SCHEMBL12226381 0.82 L3MBTL1 (0.73) SMN1; SMN2NPC1RAB9AKMT2AMEN1
SCHEMBL11356431 0.82 L3MBTL1 (0.73) PDK1PDK2PDK3PDK4SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8151705-B2 Method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-8012671-B2 Curable composition, image forming material, and planographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-09-06 US disclosed
US-7989140-B2 Curable composition, image forming material, and planographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-08-02 US disclosed
US-7964334-B2 Mixture containing urea compound as photoinitiator; curing by exposure to laser light FUJIFILM CORPORATION (JP) 2011-06-21 US disclosed
US-7955781-B2 Negative-working photosensitive material and negative-working planographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-06-07 US disclosed
US-7883827-B2 acrylate copolymer binder has superior developing properties while suppressing damages resulting from permeation of the developer caused by the acid content; for use with a laser beam; excellent in printing durability and image formation FUJIFILM CORPORATION (JP) 2011-02-08 US disclosed
US-7771916-B2 Polymerizable composition and planographic printing plate precursor FUJIFILM CORPORATION (JP) 2010-08-10 US disclosed
US-20100081771-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed
US-20090263588-A1 PHOTOCURABLE COATING COMPOSITION, AND OVERPRINT AND PROCESS FOR PRODUCING SAME FUJIFILM CORPORATION (JP) 2009-10-22 US disclosed
US-20090087780-A1 NEGATIVE-WORKING PHOTOSENSITIVE MATERIAL AND NEGATIVE-WORKING PLANOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20090087788-A1 CURABLE COMPOSITION, IMAGE FORMING MATERIAL, AND PLANOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20090075206-A1 CURABLE COMPOSITION, IMAGE FORMING MATERIAL, AND PLANOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-03-19 US disclosed
US-20080241744-A1 CURABLE COMPOSITION AND PLANOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed
US-7338748-B2 Polymerizable composition and planographic printing plate precursor FUJIFILM CORPORATION (JP) 2008-03-04 US disclosed
US-20070202439-A1 Polymerizable composition and planographic printing plate precursor FUJIFILM CORPORATION 2007-08-30 US disclosed